一个罕见的酒精性肝病并发继发性 IgA 血管炎肾炎的病例,表现为快速进展性肾小球肾炎。

Shruthi Muralidharan, Gerry George Mathew, Varadharajan Jayaprakash, Sreedhar Sailapathy
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摘要

IgA 肾病(IgAN)是酒精性肝病的常见并发症。然而,IgA 血管炎(IgAV)与酒精性肝硬化的关系并不常见,文献中仅有少数病例报道。继发性 IgAN 通常表现平和,在 5-25 年内缓慢发展。它通常对类固醇治疗有反应,极少进展为终末期肾病。在这里,我们介绍一名 50 多岁的男性患者,他患有高血压和酒精相关性肝硬化,因皮疹和快速进展性肾功能衰竭(RPRF)到我院就诊。他被诊断为 IgA 肾炎伴 IgA 血管炎(IgAVN)。皮肤和肾活检证实了他的诊断。由于肾功能衰竭,他开始接受肾脏替代疗法,并开始口服类固醇治疗。在接受了 6 个月的类固醇治疗后,患者痊愈并能独立透析,肾脏指标稳定。
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An Unusual Case of Alcoholic Liver Disease Associated with Secondary IgA Vasculitic Nephritis presenting as Rapidly Progressive Glomerulonephritis.

IgA nephropathy (IgAN) is a fairly common association with alcoholic liver disease. However, IgA vasculitis (IgAV) is quite an uncommon association with alcoholic liver cirrhosis and only a handful of cases have been reported in literature. Secondary IgAN usually presents in a docile manner, progressing slowly in about 5-25 years. It is usually responsive to steroid therapy, very rarely progressing to End-Stage Renal Disease. Here, we present a man in his late 50s, a known hypertensive and alcohol related liver-cirrhotic, who presented to our hospital with rash and rapidly progressive renal failure (RPRF). He was diagnosed with IgA nephritis with IgA vasculitis (IgAVN). His diagnosis was confirmed with skin and renal biopsy. He was started on renal replacement therapy for his renal failure and began oral steroid therapy. After administration of steroid therapy for 6 months, the patient recovered and was dialysis independent with stable renal parameters.

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来源期刊
CiteScore
0.70
自引率
0.00%
发文量
62
期刊介绍: Il Giornale Italiano di Nefrologia (GIN) è la rivista di educazione continua della Società Italiana di Nefrologia SIN ed è pubblicato bimestralmente. E" il più autorevole organo di informazione nefrologia disponibile a livello nazionale. Il giornale Italiano di Nefrologia offre la più aggiornata informazione medico-scientifica rivolta al nefrologo sotto forma di rassegne, casi clinici e articoli finalizzati all’Educazione Continua in Medicina, oltre ai notiziari ed agli atti dei congressi di questa prestigiosa Società Scientifica
期刊最新文献
[ANCA-Associated Glomerulonephritis Following SARS-CoV2 Infection: A Case Report]. [Governo clinico in nefrologia: organizzazione e sviluppo della dialisi peritoneale]. [Hypotension and Generalized Edema Due to Plasma Leakage: A Case Report]. [Reactive Perforating Collagenosis in Hemodialysis Patients]. [Survey and Intervention Tools for Burnout in Dialysis Healthcare Staff].
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