利用基于图谱的自动分割和脚本提高头颈部癌症放疗的轮廓处理效率

IF 1.8 4区 医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL In vivo Pub Date : 2024-07-01 DOI:10.21873/invivo.13621
Yukari Nagayasu, Shingo Ohira, Toshiki Ikawa, Akira Masaoka, Naoyuki Kanayama, Takahisa Nishi, Tanaka Kazunori, Yutaro Yoshino, Masayoshi Miyazaki, Yoshihiro Ueda, Koji Konishi
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引用次数: 0

摘要

背景/目的:调强放射治疗可以向靶点提供高度适形的剂量,同时最大限度地减少危险器官(OAR)的剂量。划定 "危险器官 "的轮廓非常耗时,目前已采用各种自动轮廓软件程序来缩短划定时间。然而,有些软件操作是手动的,因此有可能进一步缩短时间。本研究旨在使用脚本功能自动运行基于图集的自动分割(ABAS)和软件操作,从而减少工作时间:使用骰子系数和豪斯多夫距离来确定几何精度。测量了手动划线、自动划线和修改时间。在修改轮廓时,对主观修正程度进行了四点评分:结果:模型总体上表现出良好的几何精度。结果:模型的几何精确度普遍较高,但在一些局部区域,如视交叉、视神经、视网膜、晶状体和大脑等还需要改进。轮廓划定的平均时间从 57 分钟缩短到 29 分钟(p 结论:ABAS 模型和脚本自动化系统可以有效缩短轮廓划定时间:头颈部癌症的 ABAS 模型和脚本自动化减少了工作时间和软件操作。通过提高轮廓的准确性,还可以进一步缩短时间。
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Enhancing the Contouring Efficiency for Head and Neck Cancer Radiotherapy Using Atlas-based Auto-segmentation and Scripting.

Background/aim: Intensity-modulated radiation therapy can deliver a highly conformal dose to a target while minimizing the dose to the organs at risk (OARs). Delineating the contours of OARs is time-consuming, and various automatic contouring software programs have been employed to reduce the delineation time. However, some software operations are manual, and further reduction in time is possible. This study aimed to automate running atlas-based auto-segmentation (ABAS) and software operations using a scripting function, thereby reducing work time.

Materials and methods: Dice coefficient and Hausdorff distance were used to determine geometric accuracy. The manual delineation, automatic delineation, and modification times were measured. While modifying the contours, the degree of subjective correction was rated on a four-point scale.

Results: The model exhibited generally good geometric accuracy. However, some OARs, such as the chiasm, optic nerve, retina, lens, and brain require improvement. The average contour delineation time was reduced from 57 to 29 min (p<0.05). The subjective revision degree results indicated that all OARs required minor modifications; only the submandibular gland, thyroid, and esophagus were rated as modified from scratch.

Conclusion: The ABAS model and scripted automation in head and neck cancer reduced the work time and software operations. The time can be further reduced by improving contour accuracy.

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来源期刊
In vivo
In vivo 医学-医学:研究与实验
CiteScore
4.20
自引率
4.30%
发文量
330
审稿时长
3-8 weeks
期刊介绍: IN VIVO is an international peer-reviewed journal designed to bring together original high quality works and reviews on experimental and clinical biomedical research within the frames of physiology, pathology and disease management. The topics of IN VIVO include: 1. Experimental development and application of new diagnostic and therapeutic procedures; 2. Pharmacological and toxicological evaluation of new drugs, drug combinations and drug delivery systems; 3. Clinical trials; 4. Development and characterization of models of biomedical research; 5. Cancer diagnosis and treatment; 6. Immunotherapy and vaccines; 7. Radiotherapy, Imaging; 8. Tissue engineering, Regenerative medicine; 9. Carcinogenesis.
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