孤立性头部外伤后脑静脉窦血栓形成小儿患者的临床特征。

IF 2.1 3区 医学 Q3 CLINICAL NEUROLOGY Journal of neurosurgery. Pediatrics Pub Date : 2024-06-28 Print Date: 2024-09-01 DOI:10.3171/2024.4.PEDS24109
Saki Kotani, Gaku Fujiwara, Keisuke Fuji, Toyonobu Maekawa, Shogo Ogita, Yudai Goto, Mamoru Murakami, Satoshi Kimura, Nobukuni Murakami, Naoya Hashimoto
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引用次数: 0

摘要

目的:钝性头部外伤与脑静脉窦血栓形成(CVST)之间的关联已得到公认,但其症状并无特异性,症状持续时间也不明确。大多数外伤性 CVST 病例不需要抗凝治疗,但这一观点存在争议。本研究旨在描述孤立性头部外伤后 CVST 儿童的临床特征和预后:回顾性审查了 2018 年 1 月至 2023 年 5 月期间在 3 个医疗中心接受观察的孤立性头部创伤儿科患者的病历。CVST通过磁共振静脉造影(MRV)确诊。对随访 MRV 的患者的临床表现、治疗管理和结果进行了评估:在 3 家医院收治的 260 名头部外伤儿科患者中,26 名患者接受了 MRV 检查,8 名(30.8%)患者被诊断为 CVST。一名患者接受了肝素治疗,其他患者则接受了保守治疗。所有患者均无症状出院回家。随访期间进行的磁共振成像检查显示,除一例部分再通外,所有病例均完全再通。CVST患者的中位住院时间比无CVST患者长(9.5天对3.0天,P = 0.001):结论:外伤性 CVST 儿童患者的住院时间比无 CVST 患者长,但大多数患者在保守治疗后都能自发再通,疗效良好。
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Clinical features of pediatric patients with cerebral venous sinus thrombosis after isolated head trauma.

Objective: An association between blunt head trauma and cerebral venous sinus thrombosis (CVST) has been recognized, but its symptoms are nonspecific and the duration of symptoms remains unclear. Anticoagulation therapy is not considered necessary in most cases of traumatic CVST; however, this is controversial. The aim of this study was to describe the clinical characteristics and outcomes of children with CVST after isolated head trauma.

Methods: The records of pediatric patients with isolated head trauma admitted for observation at 3 medical centers between January 2018 and May 2023 were reviewed retrospectively. CVST was diagnosed on MR venography (MRV). Clinical presentation, therapeutic management, and outcomes were evaluated in patients who had follow-up MRV.

Results: Of 260 pediatric patients with head trauma admitted to the 3 hospitals, 26 patients underwent MRV and 8 (30.8%) were diagnosed with CVST. One patient was treated with heparin, while the others received conservative treatment. All patients were discharged home asymptomatic. MRV performed during follow-up displayed complete recanalization in all cases, except for 1 case with partial recanalization. The median hospital stay was longer in patients with CVST than in those without CVST (9.5 vs 3.0 days, p = 0.001).

Conclusions: The length of stay of pediatric patients with traumatic CVST was prolonged compared with those without CVST, but most patients had good outcomes with spontaneous recanalization following conservative treatment.

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来源期刊
Journal of neurosurgery. Pediatrics
Journal of neurosurgery. Pediatrics 医学-临床神经学
CiteScore
3.40
自引率
10.50%
发文量
307
审稿时长
2 months
期刊介绍: Information not localiced
期刊最新文献
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