血管内分裂瘤是静脉阻塞的极不寻常原因:病例报告。

IF 1.7 Q3 PATHOLOGY Journal of Pathology and Translational Medicine Pub Date : 2024-09-01 Epub Date: 2024-07-03 DOI:10.4132/jptm.2024.05.15
Luis Miguel Chinchilla-Tábora, Beatriz Segovia Blázquez, José María Sayagués, Marta Rodríguez González, Joaquín González-Rivero, José Antonio Muñoz León, Andrea Beatriz Jiménez Pérez, Idalia González Morais, Diego Bueno-Sacristán, María Dolores Ludeña
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引用次数: 0

摘要

血管腔是像裂孔瘤这样的良性周围神经鞘瘤极为罕见的部位。此前报道的病例不到 10 例。在本报告中,我们介绍了一例 68 岁女性的病例,她在体检时发现左腿后侧小腿处有一个软组织结节。完全手术切除后进行了病理检查。患者术后随访 12 个月,未发现复发或其他并发症。这是首例血管内分裂瘤导致静脉阻塞的病例。显微镜下,肿瘤由Schwann纺锤形细胞组成,对S100蛋白和SOX10有免疫反应。肿瘤周围有界限清晰的血管平滑肌壁。需要进行前瞻性的系列研究,以加深对血管内分裂瘤发生机制的了解。
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Intravascular schwannoma as an extremely unusual cause of vein obstruction: a case report.

The blood vessel lumen is an extremely rare location for a benign peripheral nerve sheath tumor like schwannoma. Less than 10 cases have been previously reported. In this report, we present a case of a 68-year-old woman who had a soft tissue nodule at the posterior calf of her left leg during a physical examination. Pathological examination was performed after complete surgical excision. The patient underwent follow-up for 12 months after surgery without evidence of recurrence or any other complication. This is the first case of intravascular schwannoma reported as a cause of vein obstruction. Microscopically, the tumor was composed of Schwann spindle cells that were immunoreactive for S100 protein and SOX10. This tumor was surrounded by a well-defined vascular smooth muscle wall. Prospective series are required to improve the knowledge on the underlying mechanisms of intravascular schwannoma development.

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来源期刊
CiteScore
5.00
自引率
4.20%
发文量
45
审稿时长
14 weeks
期刊介绍: The Journal of Pathology and Translational Medicine is an open venue for the rapid publication of major achievements in various fields of pathology, cytopathology, and biomedical and translational research. The Journal aims to share new insights into the molecular and cellular mechanisms of human diseases and to report major advances in both experimental and clinical medicine, with a particular emphasis on translational research. The investigations of human cells and tissues using high-dimensional biology techniques such as genomics and proteomics will be given a high priority. Articles on stem cell biology are also welcome. The categories of manuscript include original articles, review and perspective articles, case studies, brief case reports, and letters to the editor.
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