一名小男孩肉样瘤病的罕见表现。

Sarah Nalliannan, Shyamala Jayamoorthy, Mahesh Janarthanan
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摘要

肉样瘤病是一种病因不明的慢性多系统肉芽肿性疾病。在幼儿中很少见。一名 9 岁男孩自 5 岁起出现发育不良、皮疹、持续发热和呼吸道症状。血液检查显示血钙和血管紧张素转换酶水平升高,左侧胫骨皮疹活检显示为非结痂性肉芽肿病变。胸部计算机断层扫描显示患有间质性肺病,眼部检查显示患有双侧葡萄膜炎。他还患有感音神经性听力障碍、肾钙化和身材矮小。患者接受了口服类固醇和霉酚酸酯治疗。随访发现,他的皮疹和关节炎等全身症状有所改善。肉样瘤病的早期发现、诊断和适当治疗对于控制病情和避免发病至关重要。
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Rare manifestations of sarcoidosis in a young boy.

Sarcoidosis is a chronic multisystem granulomatous disease of unknown etiology. It is rare in young children. A 9-year-old boy presented with failure to thrive, skin rashes, persistent fever, and respiratory symptoms since 5 years of age. Blood investigations done showed elevated serum calcium and angiotensin converting enzyme levels and biopsy of the rashes on the left shin revealed non-caseating granulomatous lesion. Computed tomography of chest revealed interstitial lung disease and examination of eyes showed bilateral uveitis. He also had sensorineural hearing impairment, nephrocalcinosis, and short stature. The patient was treated with oral steroids and mycophenolate mofetil. At follow up, there was improvement in his systemic features including rashes and arthritis. Early detection, diagnosis, and appropriate treatment of sarcoidosis are vital for disease control and to avoid morbidity.

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