经皮超声引导药物注射,一种治疗声门下狭窄的潜在技术。

IF 3.5 3区 医学 Q2 RESPIRATORY SYSTEM Respiration Pub Date : 2024-01-01 Epub Date: 2024-06-27 DOI:10.1159/000539974
Mingming Deng, Run Tong, Jieru Lin, Yiding Bian, Guowu Zhou, Felix J F Herth, Gang Hou
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引用次数: 0

摘要

简介声门下狭窄表现为肉芽组织增生,具有挑战性,有时需要多次重复治疗和支架维护。皮质类固醇具有抗纤维化和抗炎特性,可预防严重声门下狭窄的发生。粘膜下注射糖皮质激素或丝裂霉素是一种有效的辅助治疗方法,可缩短内镜手术的平均间隔时间,降低气道再狭窄的风险:我们报告了一例罕见的复杂声门下狭窄男性患者的病例,该患者接受了球囊扩张联合冷冻治疗、支架置入和粘膜下曲安奈德注射辅助治疗。在经皮超声引导下,药物被高效、安全地注射到黏膜下层,声门下狭窄得到了很好的控制,且费用低廉:结论:POCUS 引导下的药物注射可能是治疗声门下狭窄的有效辅助医疗手段。
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Percutaneous Ultrasound-Guided Medication Injection: A Potential Technique for Subglottic Stenosis.

Introduction: Subglottic stenosis, manifested by granulation tissue hyperplasia, is challenging and requires multiple repeated treatments and stent maintenance at times. Corticosteroids prevent severe subglottic stenosis development owing to their antifibrotic and anti-inflammatory properties. Submucosal injection of glucocorticoids, a useful adjuvant therapeutic method, improves the mean interval between endoscopic procedures and reduces airway restenosis risks.

Case presentation: We report a rare case of a man with complex subglottic stenosis who underwent balloon dilatation combined with cryotherapy, stent placement, and adjuvant submucosal triamcinolone injection. The drug was injected efficiently and safely into the submucosal layer under percutaneous ultrasound guidance, and subglottic stenosis was well-controlled at a low cost.

Conclusion: POCUS-guided medication injections may be a useful adjuvant medical therapy for subglottic stenosis.

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来源期刊
Respiration
Respiration 医学-呼吸系统
CiteScore
7.30
自引率
5.40%
发文量
82
审稿时长
4-8 weeks
期刊介绍: ''Respiration'' brings together the results of both clinical and experimental investigations on all aspects of the respiratory system in health and disease. Clinical improvements in the diagnosis and treatment of chest and lung diseases are covered, as are the latest findings in physiology, biochemistry, pathology, immunology and pharmacology. The journal includes classic features such as editorials that accompany original articles in clinical and basic science research, reviews and letters to the editor. Further sections are: Technical Notes, The Eye Catcher, What’s Your Diagnosis?, The Opinion Corner, New Drugs in Respiratory Medicine, New Insights from Clinical Practice and Guidelines. ''Respiration'' is the official journal of the Swiss Society for Pneumology (SGP) and also home to the European Association for Bronchology and Interventional Pulmonology (EABIP), which occupies a dedicated section on Interventional Pulmonology in the journal. This modern mix of different features and a stringent peer-review process by a dedicated editorial board make ''Respiration'' a complete guide to progress in thoracic medicine.
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