经尿道水蒸气疗法(Rezūm)治疗继发于良性前列腺增生症的导管依赖型男性:一项针对香港人群的回顾性研究

IF 0.3 4区 医学 Q4 SURGERY Surgical Practice Pub Date : 2024-04-26 DOI:10.1111/1744-1633.12689
Henry Chow MBChB, FRCSEd (Urol), FCSHK, FHAKM (Surgery), Chi Ho Ip MBBS, FRCSEd (Urol), FCSHK, FHAKM (Surgery), Yiu Chung Lam MBBS, FRCSEd (Urol), FCSHK, FHAKM (Surgery)
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引用次数: 0

摘要

目的 Rezūm 是一种新型疗法,用于治疗因良性前列腺增生症(BPH)而出现中度至重度下尿路症状的患者。最近,该疗法已扩展至尿潴留导致导尿管依赖的患者,并在白人中取得了良好的效果。然而,目前还不清楚 Rezūm 在中国人群中的效果如何。在此,我们报告了对导尿管依赖性前列腺增生症中国男性患者实施 Rezūm 的经验,并对其安全性和有效性进行了评估。 方法 对 2022 年 1 月至 8 月期间接受 Rezūm 的导管依赖性良性前列腺增生症患者进行回顾性研究。我们评估了无导管试验(TWOC)的成功率,并比较了术前、术后(6 个月)的尿流率、国际前列腺症状评分(IPSS)、IPSS 生活质量评分(IPSS QoL)和前列腺体积。 结果 63 名患者接受了 Rezūm 手术(分别有 44 和 19 名患者患有难治性尿潴留和梗阻性尿病),平均年龄 74 岁,平均前列腺体积 53.9 毫升。53 名患者(85.5%;范围为术后 15-44 天)首次尝试 TWOC 成功。术后 98 天,所有患者都能自主排尿。6 个月的随访显示,IPSS 和 IPSS QoL 评分分别平均下降了 9.0 分和 1.8 分(P 均为 0.01)。术前平均排出的术后残余尿量减少了 559 毫升(P < .01),前列腺体积平均缩小了 9.4 毫升(P < .01)。七名患者在术后 30 天内出现了非严重并发症(1-2 级 Clavien-Dindo 分级)。 结论 Rezūm 对依赖导管的中国男性良性前列腺增生症患者有效且安全。
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Transurethral water vapour therapy (Rezūm) for catheter-dependent men secondary to benign prostatic hyperplasia: A retrospective study in a Hong Kong population

Aim

Rezūm is a novel treatment for patients with moderate to severe lower urinary tract symptoms as a result of benign prostatic hyperplasia (BPH). Recently, it has expanded to patients with urinary retention causing catheter dependence and the results are promising in Whites. However, it is unclear how effective Rezūm is in the Chinese population. Here, we report our experience in performing Rezūm on catheter-dependent Chinese men with BPH and evaluate its safety and efficacy.

Methods

A retrospective review of catheter-dependent patients with BPH who underwent Rezūm from January to August 2022 was conducted. We evaluated the success rate of trial without catheter (TWOC) and compared pre- and post-operative (at 6 months) uroflowmetry results, International Prostate Symptoms Score (IPSS), IPSS Quality of Life Score (IPSS QoL), and prostate volume.

Results

Sixty-three patients had Rezūm performed (44 and 19 patients had refractory urinary retention and obstructive uropathy, respectively) with a mean age of 74 years and a mean prostate size of 53.9 mL. The first attempt at TWOC was successful in 53 patients (85.5%; range 15–44 days post-operation). By 98 days after the operation, all patients could void spontaneously. The 6-month follow-up showed that IPSS and IPSS QoL scores decreased by a mean of 9.0 and 1.8 points, respectively (both P < .01). The mean pre-operative post-voided residual urine was reduced by 559 mL (P < .01), with a mean prostate size reduction of 9.4 mL (P < .01). Seven patients had non-serious complications (Grade 1–2 Clavien–Dindo classification) within 30 days of operation.

Conclusion

Rezūm was shown to be effective and safe in catheter-dependent Chinese men with BPH.

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来源期刊
Surgical Practice
Surgical Practice 医学-外科
CiteScore
0.90
自引率
0.00%
发文量
74
审稿时长
>12 weeks
期刊介绍: Surgical Practice is a peer-reviewed quarterly journal, which is dedicated to the art and science of advances in clinical practice and research in surgery. Surgical Practice publishes papers in all fields of surgery and surgery-related disciplines. It consists of sections of history, leading articles, reviews, original papers, discussion papers, education, case reports, short notes on surgical techniques and letters to the Editor.
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