与左心房阑尾闭塞器相关的感染性心内膜炎:当代系统性综述。

IF 2.1 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Journal of Interventional Cardiac Electrophysiology Pub Date : 2024-11-01 Epub Date: 2024-07-03 DOI:10.1007/s10840-024-01838-3
Alejandro Sanchez-Nadales, Muftawu Iddrisu, Roshan Wardak, Genesis M Arriola, Jose Baez-Escudero, Bo Xu
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引用次数: 0

摘要

背景:有关左房阑尾闭塞(LAAO)装置手术并发感染性心内膜炎(IE)的数据有限。本系统性综述探讨了 LAAO 术后感染性心内膜炎(IE)的病因、诊断和处理:方法:对 2007 年至 2022 年间的六个数据库进行了全面检索。在选择研究时,如果文章提供了有关 LAAO 并发 IE 的信息以及相关的临床和影像学细节,则将其纳入研究范围。如果文章是社论、研究方案、信件或摘要,则排除在外:结果:我们发现了2007年至2022年期间发表的七例美国和欧洲的LAAO并发IE病例,这突显出该病症的报告发病率极为罕见。金黄色葡萄球菌是 LAAO 感染的主要病原体。超声心动图是诊断 LAAO IE 的主要成像方式。抗生素治疗和对合适患者的手术干预对于控制 LAAO 装置相关 IE 非常重要:目前文献中有关 LAAO IE 的数据有限,这突出表明需要进行前瞻性临床试验,以建立以证据为基础的感染预防、诊断和管理指南。我们的研究结果强调了警惕器械相关感染的重要性,尤其是随着 LAAO 器械的使用在全球范围内持续增长。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Infective endocarditis associated with left atrial appendage occlusion device: a contemporary systematic review.

Background: Data are limited regarding infective endocarditis (IE) complicating left atrial appendage occlusion (LAAO) device procedures. This systematic review examines the etiology, diagnosis, and management of infective endocarditis (IE) following LAAO.

Methods: A comprehensive search of six databases was performed between 2007 and 2022. In selecting studies, articles were included if they provided information about IE complicating LAAO, with relevant clinical and imaging details. Articles were excluded if they were editorials, study protocols, letters, or abstracts.

Results: We identified seven cases of IE complicating LAAO published between 2007 and 2022, from the United States and Europe, highlighting the exceedingly rare reported incidence of the condition. Staphylococcus aureus is the predominant organism implicated in LAAO infections. Echocardiography is a key imaging modality for diagnosing LAAO IE. Both antibiotic therapy and surgical intervention in appropriate patients are important for managing LAAO device-related IE.

Conclusions: The limited data in the current literature regarding LAAO IE underscores the need for prospective clinical trials to establish evidence-based guidelines for infection prophylaxis, diagnosis, and management. Our findings emphasize the importance of vigilance for device-related infections, especially as the use of LAAO devices continues to grow worldwide.

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来源期刊
CiteScore
4.30
自引率
11.10%
发文量
320
审稿时长
4-8 weeks
期刊介绍: The Journal of Interventional Cardiac Electrophysiology is an international publication devoted to fostering research in and development of interventional techniques and therapies for the management of cardiac arrhythmias. It is designed primarily to present original research studies and scholarly scientific reviews of basic and applied science and clinical research in this field. The Journal will adopt a multidisciplinary approach to link physical, experimental, and clinical sciences as applied to the development of and practice in interventional electrophysiology. The Journal will examine techniques ranging from molecular, chemical and pharmacologic therapies to device and ablation technology. Accordingly, original research in clinical, epidemiologic and basic science arenas will be considered for publication. Applied engineering or physical science studies pertaining to interventional electrophysiology will be encouraged. The Journal is committed to providing comprehensive and detailed treatment of major interventional therapies and innovative techniques in a structured and clinically relevant manner. It is directed at clinical practitioners and investigators in the rapidly growing field of interventional electrophysiology. The editorial staff and board reflect this bias and include noted international experts in this area with a wealth of expertise in basic and clinical investigation. Peer review of all submissions, conflict of interest guidelines and periodic editorial board review of all Journal policies have been established.
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