Jing-Hua Zuo, Xiao-Yu Che, Bin-Bin Tan, Yan Jiang, Jie Bai, Xue-Lei Li, Yi-Shi Yang, Shu-Jie Pang, Xing-Chao Liu, Hai-Ning Fan, Cheng-Cheng Zhang, Jing-Jing Wang, Yan-Qi Zhang, Hai-Su Dai, Zhi-Yu Chen, Lang Gan, Zhi-Peng Liu
{"title":"采用根治性切除术治疗的肝周胆管癌患者术前体重指数与手术感染之间的关系:一项多中心研究","authors":"Jing-Hua Zuo, Xiao-Yu Che, Bin-Bin Tan, Yan Jiang, Jie Bai, Xue-Lei Li, Yi-Shi Yang, Shu-Jie Pang, Xing-Chao Liu, Hai-Ning Fan, Cheng-Cheng Zhang, Jing-Jing Wang, Yan-Qi Zhang, Hai-Su Dai, Zhi-Yu Chen, Lang Gan, Zhi-Peng Liu","doi":"10.1089/sur.2023.382","DOIUrl":null,"url":null,"abstract":"<p><p><b><i>Background:</i></b> The objective of this study was to investigate the association between pre-operative body mass index (BMI) and surgical infection in perihilar cholangiocarcinoma (pCCA) patients treated with curative resection. <b><i>Methods:</i></b> Consecutive pCCA patients were enrolled from four tertiary hospitals between 2008 and 2022. According to pre-operative BMI, the patients were divided into three groups: low BMI (≤18.4 kg/m<sup>2</sup>), normal BMI (18.5-24.9 kg/m<sup>2</sup>), and high BMI (≥25.0 kg/m<sup>2</sup>). The incidence of surgical infection among the three groups was compared. Multivariable logistic regression models were used to determine the independent risk factors associated with surgical infection. <b><i>Results:</i></b> A total of 371 patients were enrolled, including 283 patients (76.3%) in the normal BMI group, 30 patients (8.1%) in the low BMI group, and 58 patients (15.6%) in the high BMI group. The incidence of surgical infection was significantly higher in the patients in the low BMI and high BMI groups than in the normal BMI group. The multivariable logistic regression model showed that low BMI and high BMI were independently associated with the occurrence of surgical infection. <b><i>Conclusions:</i></b> The pCCA patients with a normal BMI treated with curative resection could have a lower risk of surgical infection than pCCA patients with an abnormal BMI.</p>","PeriodicalId":22109,"journal":{"name":"Surgical infections","volume":null,"pages":null},"PeriodicalIF":1.4000,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Association between Pre-operative Body Mass Index and Surgical Infection in Perihilar Cholangiocarcinoma Patients Treated with Curative Resection: A Multi-center Study.\",\"authors\":\"Jing-Hua Zuo, Xiao-Yu Che, Bin-Bin Tan, Yan Jiang, Jie Bai, Xue-Lei Li, Yi-Shi Yang, Shu-Jie Pang, Xing-Chao Liu, Hai-Ning Fan, Cheng-Cheng Zhang, Jing-Jing Wang, Yan-Qi Zhang, Hai-Su Dai, Zhi-Yu Chen, Lang Gan, Zhi-Peng Liu\",\"doi\":\"10.1089/sur.2023.382\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b><i>Background:</i></b> The objective of this study was to investigate the association between pre-operative body mass index (BMI) and surgical infection in perihilar cholangiocarcinoma (pCCA) patients treated with curative resection. <b><i>Methods:</i></b> Consecutive pCCA patients were enrolled from four tertiary hospitals between 2008 and 2022. According to pre-operative BMI, the patients were divided into three groups: low BMI (≤18.4 kg/m<sup>2</sup>), normal BMI (18.5-24.9 kg/m<sup>2</sup>), and high BMI (≥25.0 kg/m<sup>2</sup>). The incidence of surgical infection among the three groups was compared. Multivariable logistic regression models were used to determine the independent risk factors associated with surgical infection. <b><i>Results:</i></b> A total of 371 patients were enrolled, including 283 patients (76.3%) in the normal BMI group, 30 patients (8.1%) in the low BMI group, and 58 patients (15.6%) in the high BMI group. The incidence of surgical infection was significantly higher in the patients in the low BMI and high BMI groups than in the normal BMI group. The multivariable logistic regression model showed that low BMI and high BMI were independently associated with the occurrence of surgical infection. <b><i>Conclusions:</i></b> The pCCA patients with a normal BMI treated with curative resection could have a lower risk of surgical infection than pCCA patients with an abnormal BMI.</p>\",\"PeriodicalId\":22109,\"journal\":{\"name\":\"Surgical infections\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2024-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Surgical infections\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1089/sur.2023.382\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/7/3 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"INFECTIOUS DISEASES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Surgical infections","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1089/sur.2023.382","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/7/3 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
Association between Pre-operative Body Mass Index and Surgical Infection in Perihilar Cholangiocarcinoma Patients Treated with Curative Resection: A Multi-center Study.
Background: The objective of this study was to investigate the association between pre-operative body mass index (BMI) and surgical infection in perihilar cholangiocarcinoma (pCCA) patients treated with curative resection. Methods: Consecutive pCCA patients were enrolled from four tertiary hospitals between 2008 and 2022. According to pre-operative BMI, the patients were divided into three groups: low BMI (≤18.4 kg/m2), normal BMI (18.5-24.9 kg/m2), and high BMI (≥25.0 kg/m2). The incidence of surgical infection among the three groups was compared. Multivariable logistic regression models were used to determine the independent risk factors associated with surgical infection. Results: A total of 371 patients were enrolled, including 283 patients (76.3%) in the normal BMI group, 30 patients (8.1%) in the low BMI group, and 58 patients (15.6%) in the high BMI group. The incidence of surgical infection was significantly higher in the patients in the low BMI and high BMI groups than in the normal BMI group. The multivariable logistic regression model showed that low BMI and high BMI were independently associated with the occurrence of surgical infection. Conclusions: The pCCA patients with a normal BMI treated with curative resection could have a lower risk of surgical infection than pCCA patients with an abnormal BMI.
期刊介绍:
Surgical Infections provides comprehensive and authoritative information on the biology, prevention, and management of post-operative infections. Original articles cover the latest advancements, new therapeutic management strategies, and translational research that is being applied to improve clinical outcomes and successfully treat post-operative infections.
Surgical Infections coverage includes:
-Peritonitis and intra-abdominal infections-
Surgical site infections-
Pneumonia and other nosocomial infections-
Cellular and humoral immunity-
Biology of the host response-
Organ dysfunction syndromes-
Antibiotic use-
Resistant and opportunistic pathogens-
Epidemiology and prevention-
The operating room environment-
Diagnostic studies