扩大手性药物和手性纳米材料作为潜在治疗工具的作用。

IF 2.8 4区 化学 Q2 CHEMISTRY, ANALYTICAL Chirality Pub Date : 2024-07-04 DOI:10.1002/chir.23698
Sourabh Satapathy, Shivam Kumar, Balak Das Kurmi, Ghanshyam Das Gupta, Preeti Patel
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引用次数: 0

摘要

手性是分子具有镜像形式的特性,在制药和生物医学研究中发挥着至关重要的作用。本综述突出了手性日益增长的重要性,强调了手性药物和纳米材料如何影响药物的有效性、安全性和诊断。手性分子可作为精确的诊断工具,通过独特的生物分子相互作用帮助准确检测疾病。文章广泛介绍了手性药物在治疗心血管疾病、中枢神经系统疾病、局部麻醉、消炎药、抗菌药和抗癌药方面的应用。此外,文章还探讨了新兴的手性纳米材料领域,重点介绍了它们在诊断和治疗方面的生物医学应用,从而提高了医疗效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Expanding the Role of Chiral Drugs and Chiral Nanomaterials as a Potential Therapeutic Tool

Chirality, the property of molecules having mirror-image forms, plays a crucial role in pharmaceutical and biomedical research. This review highlights its growing importance, emphasizing how chiral drugs and nanomaterials impact drug effectiveness, safety, and diagnostics. Chiral molecules serve as precise diagnostic tools, aiding in accurate disease detection through unique biomolecule interactions. The article extensively covers chiral drug applications in treating cardiovascular diseases, CNS disorders, local anesthesia, anti-inflammatories, antimicrobials, and anticancer drugs. Additionally, it explores the emerging field of chiral nanomaterials, highlighting their suitability for biomedical applications in diagnostics and therapeutics, enhancing medical treatments.

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来源期刊
Chirality
Chirality 医学-分析化学
CiteScore
4.40
自引率
5.00%
发文量
124
审稿时长
1 months
期刊介绍: The main aim of the journal is to publish original contributions of scientific work on the role of chirality in chemistry and biochemistry in respect to biological, chemical, materials, pharmacological, spectroscopic and physical properties. Papers on the chemistry (physiochemical, preparative synthetic, and analytical), physics, pharmacology, clinical pharmacology, toxicology, and other biological aspects of chiral molecules will be published.
期刊最新文献
Chiral Differentiation of Chiral Lactides and Chiral Diketones on Native and Phenylcarbamoylated Cyclodextrin Chiral Stationary Phases. Multiwavelength Optical Rotation Detection: An Effective Approach for the Recognition of Analytical and Semi-Preparative HPLC Enantioseparation of the Chiral Pheromone Olean and Its Stereochemical Characterization Emergence of Optical Activity and Surface Morphology Changes in Racemic Amino Acid Films Under Circularly Polarized Lyman-α Light Irradiation Proceedings From 33rd Symposium on Chirality 2023, Rome, Italy Resolution and Absolute Configuration of Fargesin Enantiomers
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