{"title":"手术治疗克罗恩病肠瘘的效果。","authors":"Norifumi Hattori, Goro Nakayama, Shinichi Umeda, Masanao Nakamura, Takeshi Yamamura, Tsunaki Sawada, Koki Nakanishi, Dai Shimizu, Mitsuro Kanda, Masamichi Hayashi, Chie Tanaka, Yasuhiro Kodera","doi":"10.18999/nagjms.86.2.280","DOIUrl":null,"url":null,"abstract":"<p><p>Enterovesical fistula (EVF) in Crohn's disease (CD) often does not improve with medical treatment and requires surgical treatment. The surgical treatment strategy for EVF in CD is definitive resection of the intestinal tract side, and performing a leak test using dye injection into the bladder after EVF dissection to determine the appropriate surgical procedure for the bladder side. This study aimed to evaluate the outcomes of surgical treatment for EVF in CD. Twenty-one patients who underwent surgery for EVF between 2006 and 2021 were included and retrospectively evaluated for clinical background, surgical procedures, and postoperative complications. The most common origin of EVF was the ileum (17 cases; 81%), and the most common site of EVF formation was the apex (12; 57%). Surgical approaches were laparotomy in 11 (52%) cases and laparoscopy in 10 (48%). Surgical procedures on the bladder side were fistula dissection in 13 (62%) cases and sutured closure of fistula in 8 (38%). A comparison of approaches revealed no significant difference in operative time, but the amount of blood loss was significantly less in the laparoscopy (p < 0.01). There was no significant difference in the occurrence of postoperative complications between approaches. Postoperative anti-TNF-α antibody agents were used in 17 (81%) cases, and there were no cases of recurrent EVF. In conclusion, definitive resection of the intestinal tract and minimal treatment on the bladder side were sufficient to achieve satisfactory outcomes for EVF in CD.</p>","PeriodicalId":49014,"journal":{"name":"Nagoya Journal of Medical Science","volume":"86 2","pages":"280-291"},"PeriodicalIF":0.9000,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11219233/pdf/","citationCount":"0","resultStr":"{\"title\":\"Outcomes of surgical treatment for enterovesical fistula in Crohn's disease.\",\"authors\":\"Norifumi Hattori, Goro Nakayama, Shinichi Umeda, Masanao Nakamura, Takeshi Yamamura, Tsunaki Sawada, Koki Nakanishi, Dai Shimizu, Mitsuro Kanda, Masamichi Hayashi, Chie Tanaka, Yasuhiro Kodera\",\"doi\":\"10.18999/nagjms.86.2.280\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Enterovesical fistula (EVF) in Crohn's disease (CD) often does not improve with medical treatment and requires surgical treatment. The surgical treatment strategy for EVF in CD is definitive resection of the intestinal tract side, and performing a leak test using dye injection into the bladder after EVF dissection to determine the appropriate surgical procedure for the bladder side. This study aimed to evaluate the outcomes of surgical treatment for EVF in CD. Twenty-one patients who underwent surgery for EVF between 2006 and 2021 were included and retrospectively evaluated for clinical background, surgical procedures, and postoperative complications. The most common origin of EVF was the ileum (17 cases; 81%), and the most common site of EVF formation was the apex (12; 57%). Surgical approaches were laparotomy in 11 (52%) cases and laparoscopy in 10 (48%). Surgical procedures on the bladder side were fistula dissection in 13 (62%) cases and sutured closure of fistula in 8 (38%). A comparison of approaches revealed no significant difference in operative time, but the amount of blood loss was significantly less in the laparoscopy (p < 0.01). There was no significant difference in the occurrence of postoperative complications between approaches. Postoperative anti-TNF-α antibody agents were used in 17 (81%) cases, and there were no cases of recurrent EVF. In conclusion, definitive resection of the intestinal tract and minimal treatment on the bladder side were sufficient to achieve satisfactory outcomes for EVF in CD.</p>\",\"PeriodicalId\":49014,\"journal\":{\"name\":\"Nagoya Journal of Medical Science\",\"volume\":\"86 2\",\"pages\":\"280-291\"},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2024-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11219233/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nagoya Journal of Medical Science\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.18999/nagjms.86.2.280\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nagoya Journal of Medical Science","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.18999/nagjms.86.2.280","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
引用次数: 0
摘要
克罗恩病(CD)中的肠瘘(EVF)通常无法通过药物治疗得到改善,需要进行手术治疗。CD 肠瘘的手术治疗策略是明确切除肠道一侧,并在切除肠瘘后通过向膀胱注射染料进行渗漏试验,以确定膀胱一侧的适当手术方法。本研究旨在评估 CD 中 EVF 的手术治疗效果。研究纳入了2006年至2021年间接受EVF手术治疗的21例患者,并对其临床背景、手术过程和术后并发症进行了回顾性评估。EVF最常见的起源是回肠(17例;81%),EVF最常见的形成部位是顶端(12例;57%)。11例(52%)采用开腹手术,10例(48%)采用腹腔镜手术。膀胱一侧的手术方法有 13 例(62%)为瘘管剥离术,8 例(38%)为瘘管缝合术。通过比较两种方法,发现手术时间没有明显差异,但腹腔镜手术的失血量明显较少(P < 0.01)。不同方法的术后并发症发生率没有明显差异。术后使用抗肿瘤坏死因子-α抗体药物的有17例(81%),没有EVF复发的病例。总之,肠道的明确切除和膀胱侧的最低限度治疗足以使 CD 中的 EVF 获得满意的疗效。
Outcomes of surgical treatment for enterovesical fistula in Crohn's disease.
Enterovesical fistula (EVF) in Crohn's disease (CD) often does not improve with medical treatment and requires surgical treatment. The surgical treatment strategy for EVF in CD is definitive resection of the intestinal tract side, and performing a leak test using dye injection into the bladder after EVF dissection to determine the appropriate surgical procedure for the bladder side. This study aimed to evaluate the outcomes of surgical treatment for EVF in CD. Twenty-one patients who underwent surgery for EVF between 2006 and 2021 were included and retrospectively evaluated for clinical background, surgical procedures, and postoperative complications. The most common origin of EVF was the ileum (17 cases; 81%), and the most common site of EVF formation was the apex (12; 57%). Surgical approaches were laparotomy in 11 (52%) cases and laparoscopy in 10 (48%). Surgical procedures on the bladder side were fistula dissection in 13 (62%) cases and sutured closure of fistula in 8 (38%). A comparison of approaches revealed no significant difference in operative time, but the amount of blood loss was significantly less in the laparoscopy (p < 0.01). There was no significant difference in the occurrence of postoperative complications between approaches. Postoperative anti-TNF-α antibody agents were used in 17 (81%) cases, and there were no cases of recurrent EVF. In conclusion, definitive resection of the intestinal tract and minimal treatment on the bladder side were sufficient to achieve satisfactory outcomes for EVF in CD.
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