以 2-碘苯胺和碳化钙为原料，在 Pb/C 催化下循环合成 1-羰基-1H-吲哚

IF 1.7 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY Journal of Chemical Sciences Pub Date : 2024-06-27 DOI:10.1007/s12039-024-02286-2

Zhicai Zhao

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引用次数: 0

摘要

在可回收的10% Pb/C催化下，通过2-碘苯胺和电石的一锅反应制备了一系列1-羰基-1H-吲哚，并以良好的收率得到了相应的取代吲哚。该方案具有多个优点，包括利用可持续的低成本碳化钙、易于处理的乙炔源和可回收的 Pb/C 催化剂。图文摘要在 10% Pb/C 催化下，通过 2-iodoanilines 和碳化钙的一锅反应制备了一系列 1-羰基-1H-吲哚，从而以良好的收率合成了相应的取代吲哚。该方法具有多种优势，包括利用可持续的低成本原料、易于处理的乙炔源和可回收的铅/碳催化剂。

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Recycled Pb/C-catalyzed one-pot synthesis of 1-carbonyl-1H-indoles from 2-iodoanilines and calcium carbide

A series of 1-carbonyl-1H-indoles were prepared by 2-iodoanilines and calcium carbide in a one-pot reaction catalyzed by recyclable10% Pb/C, resulting in the corresponding substituted indoles in good yields. This protocol offers several advantages, including the utilization of sustainable, low-cost calcium carbide, an easy-to-handle acetylene source, and recyclable Pb/C catalysts.

Graphic abstract

The synthesis of a series of 1-carbonyl-1H-indoles were prepared by 2-iodoanilines and calcium carbide in a one-pot reaction catalyzed by 10% Pb/C, resulting in the corresponding substituted indoles in good yields. This protocol offers several advantages, including the utilization of sustainable, low-cost feedstock, an easy-to-handle acetylene source, and recyclable Pb/C catalysts.

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来源期刊

Journal of Chemical Sciences CHEMISTRY, MULTIDISCIPLINARY-

CiteScore

3.10

自引率

5.90%

发文量

107

审稿时长

1 months

期刊介绍： Journal of Chemical Sciences is a monthly journal published by the Indian Academy of Sciences. It formed part of the original Proceedings of the Indian Academy of Sciences – Part A, started by the Nobel Laureate Prof C V Raman in 1934, that was split in 1978 into three separate journals. It was renamed as Journal of Chemical Sciences in 2004. The journal publishes original research articles and rapid communications, covering all areas of chemical sciences. A significant feature of the journal is its special issues, brought out from time to time, devoted to conference symposia/proceedings in frontier areas of the subject, held not only in India but also in other countries.