{"title":"聚合物基质对含有二酮吡咯啉色团的生物启发荧光聚合物光学特性的影响","authors":"Xin Wei, Hang Zhang and Mingfeng Wang*, ","doi":"10.1021/acsapm.4c00930","DOIUrl":null,"url":null,"abstract":"<p >Biodegradable and fluorescent polymer materials have attracted growing research interests due to their tunable properties and various applications such as bioimaging and photonic information technologies. Fluorescent materials obtained by physically blending polymers with organic fluorophores often face the problems of aggregation-caused quenching (ACQ) and photobleaching. We previously reported a series of bioinspired fluorescent polymers covalently linked with a single fluorophore in the middle of each polymer chain, reminiscent of the structure of fluorescent proteins. However, the impact of polymer matrices on the optical properties of these fluorescent polymers remains poorly understood. In this article, we report the influences of different polyesters, containing a common fluorophore of a red fluorescent diketopyrrolopyrrole (DPP) derivative in the middle of each polymer chain, on the optical absorption, fluorescence, and photostability of these polymers in different states, including dilute solutions in a good solvent such as tetrahydrofuran, colloidal nanoparticles in water, and solid films. We further demonstrate the applications of these polymers in the form of colloidal nanoparticles as contrast agents for the fluorescence bioimaging of cells.</p>","PeriodicalId":7,"journal":{"name":"ACS Applied Polymer Materials","volume":null,"pages":null},"PeriodicalIF":4.4000,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Influence of the Polymer Matrix on the Optical Properties of Bioinspired Fluorescent Polymers Containing Diketopyrrolopyrrole Chromophores\",\"authors\":\"Xin Wei, Hang Zhang and Mingfeng Wang*, \",\"doi\":\"10.1021/acsapm.4c00930\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p >Biodegradable and fluorescent polymer materials have attracted growing research interests due to their tunable properties and various applications such as bioimaging and photonic information technologies. Fluorescent materials obtained by physically blending polymers with organic fluorophores often face the problems of aggregation-caused quenching (ACQ) and photobleaching. We previously reported a series of bioinspired fluorescent polymers covalently linked with a single fluorophore in the middle of each polymer chain, reminiscent of the structure of fluorescent proteins. However, the impact of polymer matrices on the optical properties of these fluorescent polymers remains poorly understood. In this article, we report the influences of different polyesters, containing a common fluorophore of a red fluorescent diketopyrrolopyrrole (DPP) derivative in the middle of each polymer chain, on the optical absorption, fluorescence, and photostability of these polymers in different states, including dilute solutions in a good solvent such as tetrahydrofuran, colloidal nanoparticles in water, and solid films. We further demonstrate the applications of these polymers in the form of colloidal nanoparticles as contrast agents for the fluorescence bioimaging of cells.</p>\",\"PeriodicalId\":7,\"journal\":{\"name\":\"ACS Applied Polymer Materials\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":4.4000,\"publicationDate\":\"2024-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ACS Applied Polymer Materials\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://pubs.acs.org/doi/10.1021/acsapm.4c00930\",\"RegionNum\":2,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MATERIALS SCIENCE, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Applied Polymer Materials","FirstCategoryId":"92","ListUrlMain":"https://pubs.acs.org/doi/10.1021/acsapm.4c00930","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
Influence of the Polymer Matrix on the Optical Properties of Bioinspired Fluorescent Polymers Containing Diketopyrrolopyrrole Chromophores
Biodegradable and fluorescent polymer materials have attracted growing research interests due to their tunable properties and various applications such as bioimaging and photonic information technologies. Fluorescent materials obtained by physically blending polymers with organic fluorophores often face the problems of aggregation-caused quenching (ACQ) and photobleaching. We previously reported a series of bioinspired fluorescent polymers covalently linked with a single fluorophore in the middle of each polymer chain, reminiscent of the structure of fluorescent proteins. However, the impact of polymer matrices on the optical properties of these fluorescent polymers remains poorly understood. In this article, we report the influences of different polyesters, containing a common fluorophore of a red fluorescent diketopyrrolopyrrole (DPP) derivative in the middle of each polymer chain, on the optical absorption, fluorescence, and photostability of these polymers in different states, including dilute solutions in a good solvent such as tetrahydrofuran, colloidal nanoparticles in water, and solid films. We further demonstrate the applications of these polymers in the form of colloidal nanoparticles as contrast agents for the fluorescence bioimaging of cells.
期刊介绍:
ACS Applied Polymer Materials is an interdisciplinary journal publishing original research covering all aspects of engineering, chemistry, physics, and biology relevant to applications of polymers.
The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates fundamental knowledge in the areas of materials, engineering, physics, bioscience, polymer science and chemistry into important polymer applications. The journal is specifically interested in work that addresses relationships among structure, processing, morphology, chemistry, properties, and function as well as work that provide insights into mechanisms critical to the performance of the polymer for applications.