水溶液中一水乳糖分子水合壳厚度的定量评估

IF 0.7 4区化学 Q4 CHEMISTRY, PHYSICAL Russian Journal of Physical Chemistry A Pub Date : 2024-07-02 DOI:10.1134/S0036024424700067

A. I. Knyazkova, M. S. Snegerev, A. P. Votintsev, V. V. Nikolaev, D. A. Vrazhnov, Yu. V. Kistenev

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引用次数: 0

摘要

摘要通过透射模式下的太赫兹光谱，研究了物理性质与水相似的溶剂对一水乳糖分子周围水合物外壳形成的影响。在溶解于纯净水、高稀释水溶液（HD）和含有干扰素-γ 抗体的高稀释水溶液（HD Ab to IFNg）时，一水乳糖水溶液的浓度与其水合物外壳的厚度之间建立了关系。研究发现，与其他研究溶剂相比，HD Ab to IFNg 溶剂在相同体积下可溶解更多的一水乳糖分子。

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Quantitative Assessment of the Hydrate Shell Thickness of Lactose Monohydrate Molecules in Aqueous Solutions

The effect of solvents similar in physical properties to water on the formation of a hydrate shell around lactose monohydrate molecules has been studied by terahertz spectroscopy in transmission mode. A relationship has been established between the concentration of aqueous solutions of lactose monohydrate and the thickness of its hydrate shell when dissolved in purified water, an aqueous solution of high dilution (HD) and an aqueous solution of high dilution with antibodies to interferon-gamma (HD Ab to IFNg). It was found that the solvent HD Ab to IFNg dissolves more lactose monohydrate molecules at the same volume compared to other studied solvents.

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来源期刊

Russian Journal of Physical Chemistry A 化学-物理化学

CiteScore

1.20

自引率

14.30%

发文量

376

审稿时长

5.1 months

期刊介绍： Russian Journal of Physical Chemistry A. Focus on Chemistry (Zhurnal Fizicheskoi Khimii), founded in 1930, offers a comprehensive review of theoretical and experimental research from the Russian Academy of Sciences, leading research and academic centers from Russia and from all over the world. Articles are devoted to chemical thermodynamics and thermochemistry, biophysical chemistry, photochemistry and magnetochemistry, materials structure, quantum chemistry, physical chemistry of nanomaterials and solutions, surface phenomena and adsorption, and methods and techniques of physicochemical studies.