O. V. Shapovalova, A. O. Tutnova, N. P. Neugodova, G. A. Sapozhnikova
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Review of the Modern Market of Reagents for the Detection of Bacterial Endotoxins in Drugs
A comparative study of reagents obtained from hemolymph of Atlantic and Asian horseshoe crabs proved the reliability of bacterial endotoxin determination. It is noted that the enzymatic activity of amebocyte lysate may differ in relation to standard endotoxin and natural endotoxin.
期刊介绍:
Pharmaceutical Chemistry Journal is a monthly publication devoted to scientific and technical research on the creation of new drugs and the improvement of manufacturing technology of drugs and intermediates. International contributors cover the entire spectrum of new drug research, including:
methods of synthesis;
results of pharmacological, toxicological, and biochemical studies;
investigation of structure - activity relationships in prediction of new compounds;
methods and technical facilities used; and
problems associated with the development of ecologically safe and economically feasible methods of industrial production.
In addition, analytical reviews of the international literature in the field provide coverage of the most recent developments around the world.
Pharmaceutical Chemistry Journal is a translation of the Russian journal Khimiko-Farmatsevticheskii Zhurnal. The Russian Volume Year is published in English from April.
All articles are peer-reviewed.