与精神分裂症叠加的早发性阿尔茨海默痴呆症:一例罕见病例报告。

IF 0.6 4区 医学 Q4 CLINICAL NEUROLOGY Neurocase Pub Date : 2024-08-01 Epub Date: 2024-07-05 DOI:10.1080/13554794.2024.2374544
Muhammed Emin Boylu, Elifnaz Uyar
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引用次数: 0

摘要

行为紊乱是精神分裂症的一个主要特征。然而,这并非精神分裂症所独有。最近,越来越多的人认识到,内源性精神障碍可能是神经退行性痴呆症的前驱阶段。因此,内源性精神障碍与痴呆症之间的联系已成为一个备受关注的话题。在本研究中,一位 49 岁的女性患者自 17 岁起就患有精神分裂症,尽管因进行性遗忘、行为异常和妄想而被怀疑患有器质性疾病,但经过 PET 和脑脊液的详细检查后,她被诊断为早发性阿尔茨海默病。精神分裂症并不是唯一会出现行为紊乱的疾病。当出现这种临床现象时,应考虑其他可能的原因。痴呆是其中最重要的原因之一。对于伴有行为紊乱的精神障碍,应考虑其他可能的病因,尤其是痴呆症。
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Early-onset Alzheimer dementia superimposed on schizophrenia: a rare case report.

Disorganized behavior is a primary sign of schizophrenia. Yet it is not unique to schizophrenia. Recently, there has been a growing understanding that endogenous mental disorders could be a prodromal stage of neurodegenerative dementia. As a result, the connection between endogenous mental disorders and dementia has become a subject of significant interest. In the present study, a 49-year-old female with schizophrenia since the age of 17 was diagnosed with early-onset Alzheimer's disease after a detailed examination with PET and cerebrospinal fluid, despite suspicion of organic disease due to progressive forgetfulness, abnormal behavior and delusions. Schizophrenia is not the only disorder in which disorganized behavior is seen. When such a clinical phenomenon develops, other possible causes should be considered. Dementia is one of the most important of these causes. In a psychiatric disorder with disorganized behavior, other possible causes, especially dementia, should be considered.

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来源期刊
Neurocase
Neurocase 医学-精神病学
CiteScore
1.40
自引率
12.50%
发文量
70
审稿时长
6-12 weeks
期刊介绍: Neurocase is a rapid response journal of case studies and innovative group studies in neuropsychology, neuropsychiatry and behavioral neurology that speak to the neural basis of cognition. Four types of manuscript are considered for publication: single case investigations that bear directly on issues of relevance to theoretical issues or brain-behavior relationships; group studies of subjects with brain dysfunction that address issues relevant to the understanding of human cognition; reviews of important topics in the domains of neuropsychology, neuropsychiatry and behavioral neurology; and brief reports (up to 2500 words) that replicate previous reports dealing with issues of considerable significance. Of particular interest are investigations that include precise anatomical localization of lesions or neural activity via imaging or other techniques, as well as studies of patients with neurodegenerative diseases, since these diseases are becoming more common as our population ages. Topic reviews are included in most issues.
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