保留原生尿道板和海绵体,结合口腔粘膜移植和奥兰迪阴茎皮瓣,替代分期尿道成形术治疗阴茎狭窄。

IF 1.8 3区 医学 Q3 UROLOGY & NEPHROLOGY International Journal of Urology Pub Date : 2024-10-01 Epub Date: 2024-07-05 DOI:10.1111/iju.15521
Leonidas Karapanos, Luisa Halbe, Enno Storz, Constantin Rieger, Richard Weiten, Bobirjon Ergashev, Axel Heidenreich
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引用次数: 0

摘要

目的:在狭窄的前尿道狭窄中,颊粘膜移植(BMG)与带蒂阴茎皮瓣(PSF)联合术是众所周知的替代分期尿道成形术的有效方法。我们假设,如果保留原生尿道板和邻近的海绵体,则需要更窄的皮瓣,并在不影响手术效果的情况下加强腹侧稳定性:12例阴茎尿道狭窄患者采用联合技术接受了单段式增粗尿道成形术。采用背侧镶嵌法将 BMG 缝合到海绵体上,然后将腹侧纵向 PSF 向腹侧移位,一侧缝合到瘢痕原生尿道粘膜上,另一侧缝合到 BMG 上,形成三角形的新尿道。保留的海绵体被包裹并固定在腹侧皮瓣周围:中位年龄为 47 岁(IQR 35-59),中位狭窄长度为 5 厘米(IQR 3,8-7)。手术时间中位数为 205 分钟(IQR 172-236)。中位随访时间为 38 个月(IQR 33-40),总体成功率(SR)为 91.7%,无囊变或憩室形成。有三个一过性瘘管通过长期的尿流改道而愈合。五名患者(41.7%)在尿道成形术后出现排尿后滴尿:结论:保留原生尿道板是结合移植物和皮瓣对狭窄尿道进行单阶段增粗尿道成形术的重要辅助手段,中期成功率令人满意,并发症发生率也可接受。
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Preservation of the native urethral plate and corpus spongiosum combined with buccal mucosa graft plus Orandi's penile skin flap as an alternative to staged urethroplasty for narrow penile strictures.

Objective: In narrow anterior urethral strictures, the combined buccal mucosa graft (BMG) with pedicled penile skin flap (PSF) represents a well-known effective alternative to staged urethroplasty. We hypothesized that if the native urethral plate and adjacent corpus spongiosum were preserved, a narrower flap would be needed, and reinforced ventral stability could be achieved without compromising the surgical outcome.

Methods: Twelve patients with narrow penile urethral strictures underwent single-stage augmentation urethroplasty using a combined technique. A BMG was quilted to the corpora cavernosa in a dorsal onlay approach, and a longitudinal ventral PSF was transposed ventrally and sutured to the scarred native urethral mucosa on one side and to the BMG on the other side to form a neourethra of triangular form. The preserved corpus spongiosum was wrapped and fixed around the flap ventrally.

Results: The median age was 47 years (IQR 35-59), and the median stricture length was 5 cm (IQR 3, 8-7). The median surgical time was 205 min (IQR 172-236). The overall success rate (SR) was 91.7% without sacculation or diverticula formation after a median follow-up period of 38 months (IQR 33-40). Three transient fistulas healed through prolonged urinary diversion. Five patients (41.7%) reported postvoid dribbling following urethroplasty.

Conclusion: Preservation of the native urethral plate is a valuable adjunct to the combination of graft and flap for single-stage augmentation urethroplasty for narrow urethral strictures, with satisfactory mid-term success and an acceptable complication rate.

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来源期刊
International Journal of Urology
International Journal of Urology 医学-泌尿学与肾脏学
CiteScore
4.70
自引率
11.50%
发文量
340
审稿时长
3 months
期刊介绍: International Journal of Urology is the official English language journal of the Japanese Urological Association, publishing articles of scientific excellence in urology. Submissions of papers from all countries are considered for publication. All manuscripts are subject to peer review and are judged on the basis of their contribution of original data and ideas or interpretation.
期刊最新文献
Comparative clinical trials with a novel approach: Utilizing the shiny method for investigational urothelial carcinoma therapies. Feasibility of approximate measurement of bladder volume in children using the Lilium α-200 portable bladder scanner. The role of lipidic balance on erectile dysfunction in prostate cancer patients undergoing robotic surgery. Efficacy and safety of dose-dense gemcitabine plus cisplatin as neoadjuvant chemotherapy for muscle-invasive bladder cancer. Preservation of the native urethral plate and corpus spongiosum combined with buccal mucosa graft plus Orandi's penile skin flap as an alternative to staged urethroplasty for narrow penile strictures.
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