急性心力衰竭患者接受非侵入性低水平外耳道刺激后的血压变化。

IF 2.4 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Journal of Cardiovascular Translational Research Pub Date : 2024-12-01 Epub Date: 2024-07-05 DOI:10.1007/s12265-024-10544-4

Michiaki Nagai, Keigo Dote, Masaya Kato, Shota Sasaki, Noboru Oda, Sunny S Po, Tarun W Dasari

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摘要

较高的血压（BP）变异性（BPV）被证明是心力衰竭（HF）患者不良心血管预后的有力预测因素。目前尚不清楚低水平外耳道刺激（LLTS）能否改善急性心力衰竭（AHF）患者的血压变异性。22 名急性心力衰竭患者（中位数为 80 岁，男性占 60%）被随机分配到主动组或假动作组，在 5 天内每天使用耳夹固定在耳廓（主动组）或耳垂（假动作组）上 1 小时。在主动组中，LLTS 后 SBP 的标准偏差（SD）、变异系数（CV）和δ均显著下降（均 p

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Blood Pressure Variability After Non-invasive Low-level Tragus Stimulation in Acute Heart Failure.

Higher blood pressure (BP) variability (BPV) was shown to be strong predictors of poor cardiovascular outcomes in heart failure (HF). It is currently unknown if low-level tragus stimulation (LLTS) would lead to improvement in BPV in acute HF (AHF). The 22 patients with AHF (median 80 yrs, males 60%) were randomly assigned to active or sham group using an ear clip attached to the tragus (active group) or the earlobe (sham group) for 1 h daily over 5 days. In the active group, standard deviation (SD), coefficient of variation (CV) and δ in SBP were significantly decreased after LLTS (all p < 0.05). All the changes in SD, CV and δ in SBP before and after stimulation were also significantly different between active and sham groups (all p < 0.05). This proof-of-concept study demonstrates the beneficial effects of LLTS on BPV in AHF.

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来源期刊

Journal of Cardiovascular Translational Research CARDIAC & CARDIOVASCULAR SYSTEMS-MEDICINE, RESEARCH & EXPERIMENTAL

CiteScore

6.10

自引率

2.90%

发文量

148

审稿时长

6-12 weeks

期刊介绍： Journal of Cardiovascular Translational Research (JCTR) is a premier journal in cardiovascular translational research. JCTR is the journal of choice for authors seeking the broadest audience for emerging technologies, therapies and diagnostics, pre-clinical research, and first-in-man clinical trials. JCTR''s intent is to provide a forum for critical evaluation of the novel cardiovascular science, to showcase important and clinically relevant aspects of the new research, as well as to discuss the impediments that may need to be overcome during the translation to patient care.