淋巴瘤的放射性配体疗法:过去、现在和未来。

IF 3 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING PET Clinics Pub Date : 2024-07-04 DOI:10.1016/j.cpet.2024.05.003
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引用次数: 0

摘要

20 世纪 80 年代,放射性标记细胞有助于了解血液肿瘤学的病理。20 世纪 90 年代,临床前试验评估了使用单克隆抗体(MoAbs)的放射性标记免疫疗法,如使用碘-131(Bexxar)或钇-90(Zevalin)标记的抗 CD20 制剂。由于放射性标记的 MoAbs 具有安全、持久的疗效,美国食品和药物管理局在 2000 年代批准了这些药物。尽管放射免疫疗法走过了漫长的历程,但其应用最近却有所减少。本综述将讨论放射免疫疗法的历史进程、优势与困难的辩论以及试验探索。我们将探讨放射配体疗法在血液肿瘤学中的未来发展方向,考虑可能成为下一个治疗趋势的新兴分子。
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Radioligand Therapy in Lymphoma
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来源期刊
PET Clinics
PET Clinics RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
5.70
自引率
3.80%
发文量
78
期刊介绍: As the clinical applications of positron emission tomography (PET) increase, the new PET Clinics brings together the combined expertise of leading authorities in the field to provide you incisive clinical reviews on advances in the use of PET and combined PET/CT. Published quarterly, PET Clinics provides concise, practical guidance on the clinical issues you face every day. It examines PET is effectiveness in cancer diagnosis and staging, as well as exploring PET is usefulness in the areas of dementia, myocardial viability, and other conditions. Full-color images featured throughout. Topics covered include Breast Cancer, Alzheimer is Disease and Dementia, Lymphoma, Lung Cancer, Cardiology, Pediatric Applications, Infection and Inflammation.
期刊最新文献
Contents Clinical Applications of PET Imaging in Alzheimer’s Disease CT, MRI, and PET Imaging in Patients with Traumatic Brain Injury Structural and Molecular Imaging of Aging Brain CME Accreditation Page
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