具有非线性扩散和奇异敏感性的准线性趋化系统的有界性和渐近行为,用于治疗脱发症

IF 1.4 Q2 MATHEMATICS, APPLIED Results in Applied Mathematics Pub Date : 2024-07-02 DOI:10.1016/j.rinam.2024.100473
Luxu Zhou, Fugeng Zeng, Lei Huang
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For <span><math><mrow><mi>i</mi><mo>=</mo><mn>1</mn><mo>,</mo><mn>2</mn><mo>,</mo></mrow></math></span> the parameters <span><math><mrow><msub><mrow><mi>χ</mi></mrow><mrow><mi>i</mi></mrow></msub><mo>,</mo><msub><mrow><mi>μ</mi></mrow><mrow><mi>i</mi></mrow></msub><mo>,</mo><mi>r</mi></mrow></math></span> are positive and <span><math><mrow><msub><mrow><mi>γ</mi></mrow><mrow><mi>i</mi></mrow></msub><mo>≥</mo><mn>2</mn></mrow></math></span>. The nonlinear diffusion functions <span><math><mrow><msub><mrow><mi>D</mi></mrow><mrow><mi>i</mi></mrow></msub><mrow><mo>(</mo><mi>s</mi><mo>)</mo></mrow><mo>∈</mo><msup><mrow><mi>C</mi></mrow><mrow><mn>2</mn></mrow></msup></mrow></math></span> satisfy <span><math><mrow><msub><mrow><mi>D</mi></mrow><mrow><mi>i</mi></mrow></msub><mrow><mo>(</mo><mi>s</mi><mo>)</mo></mrow><mo>⩾</mo><msup><mrow><mrow><mo>(</mo><mi>s</mi><mo>+</mo><mn>1</mn><mo>)</mo></mrow></mrow><mrow><msub><mrow><mi>α</mi></mrow><mrow><mi>i</mi></mrow></msub></mrow></msup></mrow></math></span> for all <span><math><mrow><mi>s</mi><mo>≥</mo><mn>0</mn></mrow></math></span>. We delve into analyzing the global existence and boundedness of classical solutions for the aforementioned system under specific conditions. Additionally, in the scenario where <span><math><mrow><msub><mrow><mi>γ</mi></mrow><mrow><mi>i</mi></mrow></msub><mo>=</mo><mn>2</mn></mrow></math></span>, we develop a Lyapunov functional and scrutinize its temporal evolution to ascertain the asymptotic stability of the coexistence state.</p></div>","PeriodicalId":36918,"journal":{"name":"Results in Applied Mathematics","volume":"23 ","pages":"Article 100473"},"PeriodicalIF":1.4000,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590037424000438/pdfft?md5=1c7b136d913734673823e8437fc9fa7f&pid=1-s2.0-S2590037424000438-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Boundedness and asymptotic behavior in a quasilinear chemotaxis system with nonlinear diffusion and singular sensitivity for alopecia areata\",\"authors\":\"Luxu Zhou,&nbsp;Fugeng Zeng,&nbsp;Lei Huang\",\"doi\":\"10.1016/j.rinam.2024.100473\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>This paper is concerned with a three-component quasilinear chemotaxis system with nonlinear diffusion and singular sensitivity for alopecia areata <span><span><span><math><mfenced><mrow><mtable><mtr><mtd><msub><mrow><mi>u</mi></mrow><mrow><mi>t</mi></mrow></msub><mo>=</mo><mo>∇</mo><mfenced><mrow><msub><mrow><mi>D</mi></mrow><mrow><mn>1</mn></mrow></msub><mrow><mo>(</mo><mi>u</mi><mo>)</mo></mrow><mo>∇</mo><mi>u</mi></mrow></mfenced><mo>−</mo><msub><mrow><mi>χ</mi></mrow><mrow><mn>1</mn></mrow></msub><mo>∇</mo><mfenced><mrow><mfrac><mrow><mi>u</mi></mrow><mrow><mi>w</mi></mrow></mfrac><mo>∇</mo><mi>w</mi></mrow></mfenced><mo>+</mo><mi>w</mi><mo>−</mo><msub><mrow><mi>μ</mi></mrow><mrow><mn>1</mn></mrow></msub><msup><mrow><mi>u</mi></mrow><mrow><msub><mrow><mi>γ</mi></mrow><mrow><mn>1</mn></mrow></msub></mrow></msup><mo>,</mo><mspace></mspace><mspace></mspace></mtd><mtd><mrow><mo>(</mo><mi>x</mi><mo>,</mo><mi>t</mi><mo>)</mo></mrow><mo>∈</mo><mi>Ω</mi><mo>×</mo><mrow><mo>(</mo><mn>0</mn><mo>,</mo><mi>∞</mi><mo>)</mo></mrow><mo>,</mo></mtd></mtr><mtr><mtd><msub><mrow><mi>v</mi></mrow><mrow><mi>t</mi></mrow></msub><mo>=</mo><mo>∇</mo><mfenced><mrow><msub><mrow><mi>D</mi></mrow><mrow><mn>2</mn></mrow></msub><mrow><mo>(</mo><mi>v</mi><mo>)</mo></mrow><mo>∇</mo><mi>v</mi></mrow></mfenced><mo>−</mo><msub><mrow><mi>χ</mi></mrow><mrow><mn>2</mn></mrow></msub><mo>∇</mo><mfenced><mrow><mfrac><mrow><mi>v</mi></mrow><mrow><mi>w</mi></mrow></mfrac><mo>∇</mo><mi>w</mi></mrow></mfenced><mo>+</mo><mi>w</mi><mo>+</mo><mi>r</mi><mi>u</mi><mi>v</mi><mo>−</mo><msub><mrow><mi>μ</mi></mrow><mrow><mn>2</mn></mrow></msub><msup><mrow><mi>v</mi></mrow><mrow><msub><mrow><mi>γ</mi></mrow><mrow><mn>2</mn></mrow></msub></mrow></msup><mo>,</mo><mspace></mspace><mspace></mspace></mtd><mtd><mrow><mo>(</mo><mi>x</mi><mo>,</mo><mi>t</mi><mo>)</mo></mrow><mo>∈</mo><mi>Ω</mi><mo>×</mo><mrow><mo>(</mo><mn>0</mn><mo>,</mo><mi>∞</mi><mo>)</mo></mrow><mo>,</mo></mtd></mtr><mtr><mtd><msub><mrow><mi>w</mi></mrow><mrow><mi>t</mi></mrow></msub><mo>=</mo><mi>Δ</mi><mi>w</mi><mo>+</mo><mi>u</mi><mo>+</mo><mi>v</mi><mo>−</mo><mi>w</mi><mo>,</mo><mspace></mspace><mspace></mspace></mtd><mtd><mrow><mo>(</mo><mi>x</mi><mo>,</mo><mi>t</mi><mo>)</mo></mrow><mo>∈</mo><mi>Ω</mi><mo>×</mo><mrow><mo>(</mo><mn>0</mn><mo>,</mo><mi>∞</mi><mo>)</mo></mrow><mo>,</mo></mtd></mtr><mtr><mtd><mfrac><mrow><mi>∂</mi><mi>u</mi></mrow><mrow><mi>∂</mi><mi>ν</mi></mrow></mfrac><mo>=</mo><mfrac><mrow><mi>∂</mi><mi>v</mi></mrow><mrow><mi>∂</mi><mi>ν</mi></mrow></mfrac><mo>=</mo><mfrac><mrow><mi>∂</mi><mi>w</mi></mrow><mrow><mi>∂</mi><mi>ν</mi></mrow></mfrac><mo>=</mo><mn>0</mn><mo>,</mo><mspace></mspace><mspace></mspace></mtd><mtd><mrow><mo>(</mo><mi>x</mi><mo>,</mo><mi>t</mi><mo>)</mo></mrow><mo>∈</mo><mi>∂</mi><mi>Ω</mi><mo>×</mo><mrow><mo>(</mo><mn>0</mn><mo>,</mo><mi>∞</mi><mo>)</mo></mrow><mo>,</mo></mtd></mtr><mtr><mtd><mi>u</mi><mrow><mo>(</mo><mi>x</mi><mo>,</mo><mn>0</mn><mo>)</mo></mrow><mo>=</mo><msub><mrow><mi>u</mi></mrow><mrow><mn>0</mn></mrow></msub><mrow><mo>(</mo><mi>x</mi><mo>)</mo></mrow><mo>,</mo><mi>v</mi><mrow><mo>(</mo><mi>x</mi><mo>,</mo><mn>0</mn><mo>)</mo></mrow><mo>=</mo><msub><mrow><mi>v</mi></mrow><mrow><mn>0</mn></mrow></msub><mrow><mo>(</mo><mi>x</mi><mo>)</mo></mrow><mo>,</mo><mi>w</mi><mrow><mo>(</mo><mi>x</mi><mo>,</mo><mn>0</mn><mo>)</mo></mrow><mo>=</mo><msub><mrow><mi>w</mi></mrow><mrow><mn>0</mn></mrow></msub><mrow><mo>(</mo><mi>x</mi><mo>)</mo></mrow><mo>,</mo><mspace></mspace><mspace></mspace></mtd><mtd><mi>x</mi><mo>∈</mo><mi>Ω</mi><mo>,</mo></mtd></mtr></mtable></mrow></mfenced></math></span></span></span>associated with homogeneous Neumann boundary conditions in a convex smooth bounded domain <span><math><mrow><mi>Ω</mi><mo>⊂</mo><msup><mrow><mi>R</mi></mrow><mrow><mn>2</mn></mrow></msup></mrow></math></span>. For <span><math><mrow><mi>i</mi><mo>=</mo><mn>1</mn><mo>,</mo><mn>2</mn><mo>,</mo></mrow></math></span> the parameters <span><math><mrow><msub><mrow><mi>χ</mi></mrow><mrow><mi>i</mi></mrow></msub><mo>,</mo><msub><mrow><mi>μ</mi></mrow><mrow><mi>i</mi></mrow></msub><mo>,</mo><mi>r</mi></mrow></math></span> are positive and <span><math><mrow><msub><mrow><mi>γ</mi></mrow><mrow><mi>i</mi></mrow></msub><mo>≥</mo><mn>2</mn></mrow></math></span>. The nonlinear diffusion functions <span><math><mrow><msub><mrow><mi>D</mi></mrow><mrow><mi>i</mi></mrow></msub><mrow><mo>(</mo><mi>s</mi><mo>)</mo></mrow><mo>∈</mo><msup><mrow><mi>C</mi></mrow><mrow><mn>2</mn></mrow></msup></mrow></math></span> satisfy <span><math><mrow><msub><mrow><mi>D</mi></mrow><mrow><mi>i</mi></mrow></msub><mrow><mo>(</mo><mi>s</mi><mo>)</mo></mrow><mo>⩾</mo><msup><mrow><mrow><mo>(</mo><mi>s</mi><mo>+</mo><mn>1</mn><mo>)</mo></mrow></mrow><mrow><msub><mrow><mi>α</mi></mrow><mrow><mi>i</mi></mrow></msub></mrow></msup></mrow></math></span> for all <span><math><mrow><mi>s</mi><mo>≥</mo><mn>0</mn></mrow></math></span>. We delve into analyzing the global existence and boundedness of classical solutions for the aforementioned system under specific conditions. Additionally, in the scenario where <span><math><mrow><msub><mrow><mi>γ</mi></mrow><mrow><mi>i</mi></mrow></msub><mo>=</mo><mn>2</mn></mrow></math></span>, we develop a Lyapunov functional and scrutinize its temporal evolution to ascertain the asymptotic stability of the coexistence state.</p></div>\",\"PeriodicalId\":36918,\"journal\":{\"name\":\"Results in Applied Mathematics\",\"volume\":\"23 \",\"pages\":\"Article 100473\"},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2024-07-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2590037424000438/pdfft?md5=1c7b136d913734673823e8437fc9fa7f&pid=1-s2.0-S2590037424000438-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Results in Applied Mathematics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2590037424000438\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MATHEMATICS, APPLIED\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Results in Applied Mathematics","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2590037424000438","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATHEMATICS, APPLIED","Score":null,"Total":0}
引用次数: 0

摘要

本文研究的是一个三分量准线性趋化系统,该系统具有非线性扩散和奇异敏感性,适用于脱发症ut=∇D1(u)∇u-χ1∇uw∇w+w-μ1uγ1、(x,t)∈Ω×(0,∞),vt=∇D2(v)∇v-χ2∇vw∇w+w+ruv-μ2vγ2、(x,t)∈Ω×(0,∞),wt=Δw+u+v-w,(x,t)∈Ω×(0,∞),∂u∂ν=∂v∂ν=∂w∂ν=0,(x,t)∈∂Ω×(0,∞),u(x,0)=u0(x),v(x、0)=v0(x),w(x,0)=w0(x),x∈Ω,与凸光滑有界域 Ω⊂R2 中的均相 Neumann 边界条件相关。i=1,2时,参数χi,μi,r为正且γi≥2。对于所有 s≥0,非线性扩散函数 Di(s)∈C2 满足 Di(s)⩾(s+1)αi。我们将深入分析上述系统在特定条件下经典解的全局存在性和有界性。此外,在 γi=2 的情况下,我们建立了一个 Lyapunov 函数,并仔细研究了它的时间演化,以确定共存状态的渐进稳定性。
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Boundedness and asymptotic behavior in a quasilinear chemotaxis system with nonlinear diffusion and singular sensitivity for alopecia areata

This paper is concerned with a three-component quasilinear chemotaxis system with nonlinear diffusion and singular sensitivity for alopecia areata ut=D1(u)uχ1uww+wμ1uγ1,(x,t)Ω×(0,),vt=D2(v)vχ2vww+w+ruvμ2vγ2,(x,t)Ω×(0,),wt=Δw+u+vw,(x,t)Ω×(0,),uν=vν=wν=0,(x,t)Ω×(0,),u(x,0)=u0(x),v(x,0)=v0(x),w(x,0)=w0(x),xΩ,associated with homogeneous Neumann boundary conditions in a convex smooth bounded domain ΩR2. For i=1,2, the parameters χi,μi,r are positive and γi2. The nonlinear diffusion functions Di(s)C2 satisfy Di(s)(s+1)αi for all s0. We delve into analyzing the global existence and boundedness of classical solutions for the aforementioned system under specific conditions. Additionally, in the scenario where γi=2, we develop a Lyapunov functional and scrutinize its temporal evolution to ascertain the asymptotic stability of the coexistence state.

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来源期刊
Results in Applied Mathematics
Results in Applied Mathematics Mathematics-Applied Mathematics
CiteScore
3.20
自引率
10.00%
发文量
50
审稿时长
23 days
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