埃塞俄比亚 2 型糖尿病患者高血压失控的预测因素:多中心横断面研究

Leteslase Hagos Gebreziher , Melak Gedamu Beyene , Desalew Mekonnen , Assefa Mulu Baye
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引用次数: 0

摘要

背景高血压(HTN)是 2 型糖尿病(T2DM)患者最常见的合并症。未控制的高血压是多种疾病的主要风险因素。本研究旨在确定 T2DM 患者中未控制的高血压的程度和预测因素。方法于 2021 年 9 月 19 日至 2021 年 12 月 17 日在高血压患者中开展了一项多中心横断面研究。采用逻辑回归模型确定高血压未控制的预测因素。未控制血压的定义是收缩压≥130 mmHg 和/或舒张压≥80 mmHg。参与者的平均年龄为 60.6 岁,标准差为 10.25 岁。156名参与者(39%)达到了目标血压。年龄、不坚持服药(OR;2.0;95 % CI:1.1-3.6;P = 0.02)、不减少饮食盐分(OR;2.4;95 % CI:1.5-3.8;P <;0.001)、血糖未得到控制(OR:2.4;95 % CI:1.4-4.3;P = 0.002)、肥胖(OR;3.2;95 % CI:1.2-8.7;P = 0.03)和每 4 个月及以上随访(OR;2.3;95 % CI:1.3-4.3;P = 0.049)与血压失控显著相关。年轻、不坚持服药、不减少膳食盐分、肥胖、随访时间较长、血糖控制不佳的高血压 T2DM 患者更容易出现血压失控。改善服药依从性、减少饮食中的盐分、频繁随访和血糖控制对控制高血压非常重要。
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Predictors of uncontrolled hypertension among type 2 diabetic patients in Ethiopia: Multicenter cross-sectional study

Background

Hypertension (HTN) is the commonest comorbidity among people with type 2 diabetes mellitus (T2DM). Uncontrolled HTN is a major risk factor for several diseases. This study aimed to determine the magnitude and predictors of uncontrolled HTN among T2DM patients.

Methods

A multicenter cross-sectional study was conducted among hypertensive from September 19, 2021 to 17 December 2021. Logistic regression model was conducted to identify predictors of uncontrolled HTN. Uncontrolled BP was defined by systolic BP of ≥130 mmHg and/or diastolic BP of ≥80 mmHg.

Results

A total of 400 study participants were included in the analysis, of which 208 (52 %) were females. The mean age of the participants was 60.6 with SD of 10.25 years. The target blood pressure achieved in 156 (39 %) of participants. Age, non-adherence to medications (OR; 2.0; 95 % CI: 1.1–3.6; P = 0.02), not reducing dietary salt (OR; 2.4; 95 % CI: 1.5–3.8; P < 0.001), uncontrolled blood sugar (OR:2.4; 95 % CI: 1.4–4.3; P = 0.002), obesity (OR; 3.2; 95 % CI:1.2–8.7; P = 0.03) and having every fourth month and above follow up (OR; 2.3; 95 % CI:1.3–4.3; P = 0.049) were significantly associated with uncontrolled blood pressure.

Conclusions

The target blood pressure achieved was suboptimal. Hypertensive T2DM patients who were younger, non-adherent to their medications, not reducing dietary salt, obese, with a longer frequency of follow-up, and with poor glycemic control were more likely to have uncontrolled blood pressure. Improving medication adherence, dietary salt reduction, frequent follow up and glycemic control are important to control hypertension.

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