Olivia Kuszaj , Marley Day , Matt Wronski , Kimberly Corbin , Patries Herst , Rosemary Hill , Dirk Rades , Cindy Wong , Irene Karam , Francois Gallant , Shing Fung Lee , Shirley SW. Tse , Edward Chow , Henry Wong
{"title":"用于预防放射性皮炎的 Mepitel 胶片：对其疗效、副作用、物理测量、患者和临床医生报告结果的全面审查","authors":"Olivia Kuszaj , Marley Day , Matt Wronski , Kimberly Corbin , Patries Herst , Rosemary Hill , Dirk Rades , Cindy Wong , Irene Karam , Francois Gallant , Shing Fung Lee , Shirley SW. Tse , Edward Chow , Henry Wong","doi":"10.1016/j.apjon.2024.100530","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><p>This review aimed to summarize the benefits, side effects, physics measurements, and patient- and clinician-reported outcomes of Mepitel film (MF) in preventing radiation dermatitis (RD) for cancer patients.</p></div><div><h3>Methods</h3><p>The online database PubMed was searched from inception to April 15, 2024 with the search terms “Mepitel film” or “Mepitel.” Articles of any study design evaluating MF for the prevention of RD were included. Non-human studies were excluded.</p></div><div><h3>Results</h3><p>The database search identified 119 articles and 13 of them were included in this review. Across these studies, MF was found to be beneficial in reducing RD and improved patient- and clinician-reported outcomes in breast and head and neck cancers. Side effects of MF included itchiness, acne, allergic reaction, tightness, discomfort, and poor film adherence, but patient dropouts were uncommon. MF did not cause a bolus effect or increased skin dose in physics measurements.</p></div><div><h3>Conclusions</h3><p>MF is a safe and effective intervention for preventing acute RD. It should be recommended in breast cancer patients where the data is more robust. Further research is needed to evaluate MF's efficacy on patients with different skin tones, its cost-effectiveness, and identifying patients who most benefit from MF relative to other effective interventions.</p></div>","PeriodicalId":2,"journal":{"name":"ACS Applied Bio Materials","volume":null,"pages":null},"PeriodicalIF":4.6000,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2347562524001525/pdfft?md5=bfd0db2c7c6c522ff6c4478efb027abb&pid=1-s2.0-S2347562524001525-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Mepitel film for the prevention of radiation dermatitis: A comprehensive review of its efficacy, side effects, physics measurements, patient- and clinician-reported outcomes\",\"authors\":\"Olivia Kuszaj , Marley Day , Matt Wronski , Kimberly Corbin , Patries Herst , Rosemary Hill , Dirk Rades , Cindy Wong , Irene Karam , Francois Gallant , Shing Fung Lee , Shirley SW. Tse , Edward Chow , Henry Wong\",\"doi\":\"10.1016/j.apjon.2024.100530\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><p>This review aimed to summarize the benefits, side effects, physics measurements, and patient- and clinician-reported outcomes of Mepitel film (MF) in preventing radiation dermatitis (RD) for cancer patients.</p></div><div><h3>Methods</h3><p>The online database PubMed was searched from inception to April 15, 2024 with the search terms “Mepitel film” or “Mepitel.” Articles of any study design evaluating MF for the prevention of RD were included. Non-human studies were excluded.</p></div><div><h3>Results</h3><p>The database search identified 119 articles and 13 of them were included in this review. Across these studies, MF was found to be beneficial in reducing RD and improved patient- and clinician-reported outcomes in breast and head and neck cancers. Side effects of MF included itchiness, acne, allergic reaction, tightness, discomfort, and poor film adherence, but patient dropouts were uncommon. MF did not cause a bolus effect or increased skin dose in physics measurements.</p></div><div><h3>Conclusions</h3><p>MF is a safe and effective intervention for preventing acute RD. It should be recommended in breast cancer patients where the data is more robust. Further research is needed to evaluate MF's efficacy on patients with different skin tones, its cost-effectiveness, and identifying patients who most benefit from MF relative to other effective interventions.</p></div>\",\"PeriodicalId\":2,\"journal\":{\"name\":\"ACS Applied Bio Materials\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":4.6000,\"publicationDate\":\"2024-05-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2347562524001525/pdfft?md5=bfd0db2c7c6c522ff6c4478efb027abb&pid=1-s2.0-S2347562524001525-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ACS Applied Bio Materials\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2347562524001525\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MATERIALS SCIENCE, BIOMATERIALS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Applied Bio Materials","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2347562524001525","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, BIOMATERIALS","Score":null,"Total":0}
Mepitel film for the prevention of radiation dermatitis: A comprehensive review of its efficacy, side effects, physics measurements, patient- and clinician-reported outcomes
Objective
This review aimed to summarize the benefits, side effects, physics measurements, and patient- and clinician-reported outcomes of Mepitel film (MF) in preventing radiation dermatitis (RD) for cancer patients.
Methods
The online database PubMed was searched from inception to April 15, 2024 with the search terms “Mepitel film” or “Mepitel.” Articles of any study design evaluating MF for the prevention of RD were included. Non-human studies were excluded.
Results
The database search identified 119 articles and 13 of them were included in this review. Across these studies, MF was found to be beneficial in reducing RD and improved patient- and clinician-reported outcomes in breast and head and neck cancers. Side effects of MF included itchiness, acne, allergic reaction, tightness, discomfort, and poor film adherence, but patient dropouts were uncommon. MF did not cause a bolus effect or increased skin dose in physics measurements.
Conclusions
MF is a safe and effective intervention for preventing acute RD. It should be recommended in breast cancer patients where the data is more robust. Further research is needed to evaluate MF's efficacy on patients with different skin tones, its cost-effectiveness, and identifying patients who most benefit from MF relative to other effective interventions.
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