波动介电傅立叶光谱仪和血细胞特征快速评估系统

IF 4.033 Q4 Biochemistry, Genetics and Molecular Biology Biophysics Pub Date : 2024-07-04 DOI:10.1134/s0006350924700180

A. V. Kovalev, Yu. I. Grinshtein, A. N. Maltseva, O. V. Krukova, V. G. Soukhovolsky

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引用次数: 0

摘要

本研究考虑了一种根据血液悬浮液的介电特性评估已形成元素状态的方法。提出了波动介电傅立叶光谱仪（FDFS）的设计方案，借助该仪器可以根据膜状态估算已形成的血液元素的分布情况。作为说明，描述了评估冠心病患者功能状态的实验和腹水艾氏癌对实验鼠影响的实验。实验结果表明，通过使用拟议的光谱仪，可以对疾病期间血液特征的变化进行明确估计，并确定腹水艾氏癌动物病理过程的动态变化。

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Fluctuation Dielectric Fourier Spectrometer and Rapid Evaluation of Blood Cell Characteristics

A method for assessing the state of formed elements based on the dielectric characteristics of a blood suspension is considered. A design of a fluctuation dielectric Fourier spectrometer (FDFS) is proposed, with the help of which it is possible to estimate the distribution of the formed blood elements according to their membrane state. As an illustration, experiments to assess the functional state of patients with coronary heart disease and an experiment on the effect of ascitic Ehrlich carcinoma on laboratory mice are described. It is shown that by using the proposed spectrometer, it is possible to obtain express estimates of changes in blood characteristics during diseases and to identify the dynamics of pathological processes in animals with ascitic Ehrlich carcinoma.

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来源期刊

Biophysics Biochemistry, Genetics and Molecular Biology-Biophysics

CiteScore

1.20

自引率

0.00%

发文量

期刊介绍： Biophysics is a multidisciplinary international peer reviewed journal that covers a wide scope of problems related to the main physical mechanisms of processes taking place at different organization levels in biosystems. It includes structure and dynamics of macromolecules, cells and tissues; the influence of environment; energy transformation and transfer; thermodynamics; biological motility; population dynamics and cell differentiation modeling; biomechanics and tissue rheology; nonlinear phenomena, mathematical and cybernetics modeling of complex systems; and computational biology. The journal publishes short communications devoted and review articles.