Copper-catalyzed allenynylative C–P coupling of diynylic acetates with hydrophosphoryl compounds leading to phosphorylated allenynes†

A highly efficient copper-catalyzed coupling reaction of diynylic acetates with hydrophosphoryl compounds is developed based on the concept of site-selective nucleophilic interception of copper-cumulenylidene-type intermediates. This reaction enables an expeditious synthesis of a novel class of conjugated allenynylphosphoryl compounds in good to high yields from readily available materials under mild conditions.