复发性咯血:诊断难题与管理策略--病例报告

Ashok P. Arbat, Gauri Gadge, Sweta R. Chourasia, Parimal S. Deshpande, Swapnil I. Bakamwar
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摘要

卡他性咯血(CH)是一种罕见的已知疾病,其诊断至关重要,而治疗却难以确定。在本病例报告中,2 年前在了解患者病史时发现其患有卡他性咯血。病史显示,在过去的 6 个月中,患者每个月都会在夜间咯血,并伴有呼吸困难,同时还伴有月经。在月经期间进行了一系列放射学检查和支气管镜检查后确诊。CT 扫描检查发现,右肺下叶上段有一个复杂的充满液体的囊性病变,其中有几个气灶,并伴有磨玻璃状不透明。随后的支气管镜检查显示,右肺下叶上段有活动性出血点。支气管冲洗试验显示微生物感染和恶性肿瘤均为阴性。患者接受了支气管动脉栓塞术(BAE),术后咯血停止。然而,在接受支气管动脉栓塞术两年后,咯血再次出现。患者的症状和咯血量较轻,因此不需要再次进行支气管动脉栓塞术。早些时候,由于激素疗法(HT)的副作用,患者拒绝接受这种疗法,但这次她接受了 HT。接受激素治疗 2 个月后,咯血逐渐停止。如果将来出现并发症,那么手术治疗和激素治疗(联合疗法)将是治疗方案。CH 的诊断具有挑战性,治疗程序也因人而异,因此需要量身定制。即使治疗后症状消失,激素仍会调节 CH 的复发。因此,定期随访和密切关注是至关重要的要求。
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Recurrent catamenial hemoptysis: diagnostic challenges and management strategies—a case report
Catamenial hemoptysis (CH) is a rare, known disease for which diagnosis is crucial and treatment is indefinite. In this case report, CH was identified 2 years ago while taking medical history of the patient. It has disclosed hemoptysis at night with breathlessness that was concurrent with her menses every month for the past 6 months. A series of radiological tests followed by a bronchoscopic examination during menses confirmed the diagnosis. A complex fluid-filled cystic lesion with few air foci in the right lower lobe superior segment with ground glass opacity was seen by a CT scan test. Subsequent bronchoscopy examination showed an active bleeding site at the right lower lobe superior segment. The bronchial wash tests were negative for microbial infections as well as for malignancies. Bronchial artery embolization (BAE) was done and it ceased the hemoptysis. However, it recurred after 2 years of the BAE procedure. The symptoms and amount of hemoptysis were milder; hence, repeated BAE was not required. Earlier, the patient refused hormonal therapy (HT) owing to its side effects, but this time, she accepted HT. After 2 months of HT, hemoptysis gradually ceased. If complications arise in the future, then surgical treatment along with HT (combination therapy) would be the course of treatment. The diagnosis of CH is challenging, and treatment procedures vary from patient to patient; hence, they are customised. Hormones regulate the CH recurrence even though the symptoms have ceased after treatment. Therefore, regular follow-up and close vigilance are crucial requirements.
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