体外成熟卵母细胞玻璃化后的活产。

IF 4.3 3区 材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC ACS Applied Electronic Materials Pub Date : 2024-08-01 Epub Date: 2024-07-11 DOI:10.1007/s10815-024-03200-y
Xuyen T H Le, Dung P Nguyen, Thao T Nguyen, Tien K Le, Lan N Vuong, Tuong M Ho
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引用次数: 0

摘要

女性生育力保存是一个快速发展的医学领域。在常规卵巢刺激方案后,使用体内成熟卵母细胞进行卵母细胞冷冻保存和玻璃化温育卵母细胞辅助生殖技术已取得成功。体外成熟卵母细胞经过玻璃化和加温后,其使用还很有限。电容体外成熟(CAPA-IVM)是体外成熟方案的最新改进,可提供能力更强的体外成熟卵母细胞。本病例报告描述了 CAPA-IVM 周期卵母细胞玻璃化后首次成功活产的案例。这一里程碑式的成就为扩大生育力保存的选择范围和提高希望冷冻保存卵子以供将来使用的妇女的可及性带来了重大希望。
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Live birth after vitrification of oocytes from capacitation in vitro maturation.

Female fertility preservation is a rapidly growing field in medicine. Oocyte cryopreservation and assisted reproductive technique with vitrified-warmed oocytes have been successful with in vivo matured oocytes after conventional ovarian stimulation protocols. The use of in vitro matured oocytes after vitrification and warming has been limited. Capacitation in vitro maturation (CAPA-IVM) represents the latest refinement of IVM protocols and provides in vitro matured oocytes with improved competence. This case report describes the first successful live birth following oocyte vitrification from a CAPA-IVM cycle. This milestone achievement holds a significant promise to expand fertility preservation options and improve accessibility for women wishing to cryopreserve their eggs for future use.

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4.30%
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