肝移植后的动脉高血压

IF 1.5 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Bratislava Medical Journal-Bratislavske Lekarske Listy Pub Date : 2024-01-01 DOI:10.4149/BLL_2024_88
Lubomir Skladany, Svetlana Adamcova Selcanova, Lukas Liptak, Ivana Dedinska
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引用次数: 0

摘要

动脉高血压是导致心血管不良预后的最普遍的可影响风险因素之一。这是一项对肝移植受者进行 24 小时血压测量的前瞻性分析。主要目的是通过 24 小时血压监测,确定没有动脉高血压病史但符合动脉高血压标准的肝移植后患者。次要目标是确定有多少已知接受过治疗的动脉高血压患者血压控制不理想。该组包括 88 名患者(男性,52.3%,有动脉高血压病史组:n=56,无动脉高血压病史组:n=32),测量时的平均年龄为 62.4 岁±11 岁。测量时的平均LT时间为45.2个月。通过 24 小时血压监测确诊的新动脉高血压患者占 28%。眼底高渗性变化被证实是高血压控制不理想的预测因素[OR 5 1265,P=0.0279]。另一方面,男性性别[OR 3.1840,p=0.0311]、年龄[OR 1.3347,p=0.0153]和腰围[OR 4.3490,p=0.0418]预示着需要加强降压治疗。男性的性别、年龄和腰围应增加怀疑指数,并导致放大血压控制不佳的可能性。在无法进行自动血压监测的情况下,定期检查眼底可作为动脉高血压控制不佳的替代指标(表 6,图 1,参考文献 36)。PDF 格式的文本 www.elis.sk 关键词:肝移植、动脉高血压、自动血压监测。
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Arterial hypertension after liver transplantation.

One of the most prevalent influenceable risk factors for poor cardiovascular outcome is arterial hypertension.This is a prospective analysis of liver transplant recipients in which 24-hour blood pressure (BP) measurement was performed. The primary aim was to identify post-LT (liver transplantation) patients without a history of arterial hypertension who meet the criteria for arterial hypertension using 24-hour BP monitoring. Secondary objectives were to determine how many patients with known treated arterial hypertension had suboptimal BP control. The group included 88 patients (men, 52.3%, history of arterial hypertension group: n=56, no history of arterial hypertension group: n=32) with an average age at the time of measurement of 62.4 years±11. The average time since LT at the time of measurement was 45.2 months. De novo arterial hypertension using 24-hour BP monitoring was diagnosed in 28%. Hypertonic changes in the fundus oculi were confirmed as predictor for suboptimally controlled hypertension [OR 5,1265, p=0.0279]. On the other hand, male sex [OR 3.1840, p=0.0311], together with age [OR 1.3347, p=0.0153] and waist circumference [OR 4.3490, p=0.0418] predicted the need of intensification of antihypertensive treatment. Male sex, age and waist circumference should increase the index of suspicion and lead to zoom-in on a possibility of poorly controlled blood pressure. Where automated blood pressure monitoring is unavailable, regular examination of the fundus could serve as an available surrogate marker of suboptimally controlled arterial hypertension (Tab.6, Fig. 1, Ref. 36). Text in PDF www.elis.sk Keywords: liver transplantation, arterial hypertension, automated blood pressure monitoring.

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来源期刊
CiteScore
2.60
自引率
0.00%
发文量
185
审稿时长
3-8 weeks
期刊介绍: The international biomedical journal - Bratislava Medical Journal – Bratislavske lekarske listy (Bratisl Lek Listy/Bratisl Med J) publishes peer-reviewed articles on all aspects of biomedical sciences, including experimental investigations with clear clinical relevance, original clinical studies and review articles.
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