中国的酒精性肝病:一种受复杂社会因素影响且不容忽视的疾病。

IF 3.1 3区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Journal of Clinical and Translational Hepatology Pub Date : 2024-07-28 Epub Date: 2024-05-31 DOI:10.14218/JCTH.2024.00034
Xiaofeng Feng, Nafei Huang, Yuqin Wu, Fei Gao, Xiaomei Chen, Chenyi Zhang, Bing Zhang, Tao Sun
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引用次数: 0

摘要

酒精性肝病(ALD)包括由长期过量饮酒引起的肝损伤。它最初表现为明显的肝细胞脂肪变性,可发展为脂肪性肝炎、肝纤维化和肝硬化。随着中国经济的快速发展,加之复杂的社会背景和不良酒文化的影响,中国的 ALD 患者数量显著增加,该病已成为一个不容忽视的社会和健康问题。在这篇综述中,我们简要描述了影响中国 ALD 的社会因素,并阐述了酒精性肝病与其他肝病在并发症(如肝硬化、上消化道出血、肝性脑病、肝细胞癌、成瘾和其他肝外疾病)方面的差异。我们还强调,由于 ALD 的并发症,它比其他肝病更危险、更难治疗,而且缺乏精确有效的治疗措施。此外,我们还考虑了未来可能产生的新想法和治疗方法。
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Alcoholic Liver Disease in China: A Disease Influenced by Complex Social Factors That Should Not Be Neglected.

Alcoholic liver disease (ALD) encompasses liver damage caused by chronic, excessive alcohol consumption. It manifests initially as marked hepatocellular steatosis and can progress to steatohepatitis, liver fibrosis, and cirrhosis. With China's rapid economic growth, coupled with a complex social background and the influence of a deleterious wine culture, the number of patients with ALD in China has increased significantly; the disease has become a social and health problem that cannot be ignored. In this review, we briefly described the social factors affecting ALD in China and elaborated on differences between alcoholic and other liver diseases in terms of complications (e.g., cirrhosis, upper gastrointestinal bleeding, hepatic encephalopathy, hepatocellular carcinoma, addiction, and other extrahepatic diseases). We also emphasized that ALD was more dangerous and difficult to treat than other liver diseases due to its complications, and that precise and effective treatment measures were lacking. In addition, we considered new ideas and treatment methods that may be generated in the future.

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来源期刊
Journal of Clinical and Translational Hepatology
Journal of Clinical and Translational Hepatology GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
6.40
自引率
2.80%
发文量
496
期刊最新文献
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