Winnifer Briceño, Esther Barbero, Eva Mañas, Sara González, Alberto García-Ortega, Grace Oscullo, Aldara García-Sánchez, Irene Cano-Pumarega, Miguel Ángel Martinez-Garcia, David Jimenez
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Our outcomes were: i) the STOP-Bang questionnaire's utility for risk stratification, ii) the discrimination of the STOP-Bang questionnaire categories, iii) the false negative rate of STOP-Bang questionnaire prediction, and iv) the clinical utility of the STOP-Bang questionnaire to exclude OSA. We also calculated the test performance characteristics to predict OSA.</p><p><strong>Results: </strong>During the study period, 268 patients completed a sleep study. OSA was found in 47% of patients. OSA incidence in low-, moderate-, and high-risk STOP-Bang groups was 22.4%, 48.2%, and 61.5%, respectively (P <0.001). The area under the receiver operating characteristics curve of the STOP-Bang questionnaire for risk of OSA was 0.65. The false negative rate of a low-risk STOP-Bang questionnaire result to rule out OSA was 22.4% and the clinical utility was 21.6%. 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引用次数: 0
摘要
研究目的:STOP-Bang 问卷是一种经过验证的阻塞性睡眠呼吸暂停(OSA)筛查工具。我们开展了这项研究,目的是在急性无症状肺栓塞(PE)住院患者中验证该问卷:这项前瞻性队列研究招募了连续稳定的急性 PE 患者,他们在确诊后 7 天内接受了夜间睡眠检查。我们的研究结果是:i) STOP-Bang 问卷对风险分层的实用性;ii) STOP-Bang 问卷类别的区分度;iii) STOP-Bang 问卷预测的假阴性率;iv) STOP-Bang 问卷排除 OSA 的临床实用性。我们还计算了预测 OSA 的测试性能特征:研究期间,268 名患者完成了睡眠检查。47%的患者被发现患有 OSA。在低危、中危和高危 STOP-Bang 组中,OSA 的发生率分别为 22.4%、48.2% 和 61.5%(P 结论:STOP-Bang 是一种用于排除 OSA 的方法:STOP-Bang 问卷对急性无症状 PE 住院患者 OSA 风险的判别能力较差。其假阴性率高,临床实用性低。STOP-Bang 问卷对男性的灵敏度较高,可用于排除该人群中的 OSA。
STOP-Bang questionnaire in patients hospitalized with acute symptomatic pulmonary embolism.
Study objectives: The STOP-Bang questionnaire is a validated screening tool for obstructive sleep apnea (OSA). We conducted this study to validate it among patients hospitalized with acute symptomatic pulmonary embolism (PE).
Methods: This prospective cohort study enrolled consecutive stable patients with acute PE who underwent an overnight sleep study within 7 days after diagnosis. Our outcomes were: i) the STOP-Bang questionnaire's utility for risk stratification, ii) the discrimination of the STOP-Bang questionnaire categories, iii) the false negative rate of STOP-Bang questionnaire prediction, and iv) the clinical utility of the STOP-Bang questionnaire to exclude OSA. We also calculated the test performance characteristics to predict OSA.
Results: During the study period, 268 patients completed a sleep study. OSA was found in 47% of patients. OSA incidence in low-, moderate-, and high-risk STOP-Bang groups was 22.4%, 48.2%, and 61.5%, respectively (P <0.001). The area under the receiver operating characteristics curve of the STOP-Bang questionnaire for risk of OSA was 0.65. The false negative rate of a low-risk STOP-Bang questionnaire result to rule out OSA was 22.4% and the clinical utility was 21.6%. The sensitivity was 89.8% (97.2% for men and 80.4% for women).
Conclusions: The STOP-Bang questionnaire showed poor discrimination for the risk of OSA in hospitalized patients with acute symptomatic PE. It had a high false negative rate and a low clinical utility. The STOP-Bang questionnaire had a good sensitivity in men, and might be used to rule out OSA in this population.
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