Jungeun Park, Yoosoo Chang, Jae Heon Kim, Hye Rin Choi, Ria Kwon, Ga-Young Lim, Jiin Ahn, Kye-Hyun Kim, Hoon Kim, Yun Soo Hong, Di Zhao, Juhee Cho, Eliseo Guallar, Hyun-Young Park, Seungho Ryu
{"title":"中年女性更年期阶段与膀胱过度活动症状:一项横断面研究","authors":"Jungeun Park, Yoosoo Chang, Jae Heon Kim, Hye Rin Choi, Ria Kwon, Ga-Young Lim, Jiin Ahn, Kye-Hyun Kim, Hoon Kim, Yun Soo Hong, Di Zhao, Juhee Cho, Eliseo Guallar, Hyun-Young Park, Seungho Ryu","doi":"10.1111/1471-0528.17912","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Objective</h3>\n \n <p>To examine the prevalence of overactive bladder (OAB) according to menopausal stages in middle-aged women.</p>\n </section>\n \n <section>\n \n <h3> Design</h3>\n \n <p>Cross-sectional study.</p>\n </section>\n \n <section>\n \n <h3> Setting</h3>\n \n <p>Total Healthcare Center in South Korea.</p>\n </section>\n \n <section>\n \n <h3> Population</h3>\n \n <p>Middle-aged Korean women (<i>n</i>=3469, mean age, 49.5 ± 2.9 years).</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>Menopausal stages were defined according to the Stages of Reproductive Aging Workshop +10 criteria, and menopausal symptoms were assessed using the Korean version of Menopause-Specific Quality of Life (MENQOL). Logistic regression models were used to estimate prevalence ratios with 95% confidence intervals for OAB according to menopausal stage and to assess the associations with menopausal symptoms.</p>\n </section>\n \n <section>\n \n <h3> Main Outcome Measures</h3>\n \n <p>OAB symptoms were evaluated using the Overactive Bladder Symptom Score (OABSS).</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>The prevalence of OAB increased with menopausal stage; however, the multivariable-adjusted prevalence ratios for women in menopausal transition and postmenopausal stage were insignificant (<i>p</i><sub>trend</sub> = 0.160) compared to those for premenopausal women. Among individual OAB symptoms, the multivariable-adjusted prevalence ratios for nocturia increased with menopausal stage in a dose–response manner (<i>p</i><sub>trend</sub> = 0.005 for 1 time/day; <i>p</i><sub>trend</sub> < 0.001 for ≥2 times/day). The association between menopausal stages and nocturia occurring ≥2 times/day was evident in women without OAB and with relatively high MENQOL scores, vasomotor symptoms and difficulty sleeping.</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>The prevalence of OAB, particularly nocturia, increased with menopausal stage, and the association was obvious in women with other menopausal symptoms. This finding underscores the importance of addressing nocturia as a potential menopausal symptom in middle-aged women. Further studies are required to understand the mechanisms linking OAB with menopausal symptoms in middle-aged women.</p>\n </section>\n </div>","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":"131 13","pages":"1805-1814"},"PeriodicalIF":4.7000,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Menopausal stages and overactive bladder symptoms in middle-aged women: A cross-sectional study\",\"authors\":\"Jungeun Park, Yoosoo Chang, Jae Heon Kim, Hye Rin Choi, Ria Kwon, Ga-Young Lim, Jiin Ahn, Kye-Hyun Kim, Hoon Kim, Yun Soo Hong, Di Zhao, Juhee Cho, Eliseo Guallar, Hyun-Young Park, Seungho Ryu\",\"doi\":\"10.1111/1471-0528.17912\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Objective</h3>\\n \\n <p>To examine the prevalence of overactive bladder (OAB) according to menopausal stages in middle-aged women.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Design</h3>\\n \\n <p>Cross-sectional study.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Setting</h3>\\n \\n <p>Total Healthcare Center in South Korea.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Population</h3>\\n \\n <p>Middle-aged Korean women (<i>n</i>=3469, mean age, 49.5 ± 2.9 years).</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>Menopausal stages were defined according to the Stages of Reproductive Aging Workshop +10 criteria, and menopausal symptoms were assessed using the Korean version of Menopause-Specific Quality of Life (MENQOL). Logistic regression models were used to estimate prevalence ratios with 95% confidence intervals for OAB according to menopausal stage and to assess the associations with menopausal symptoms.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Main Outcome Measures</h3>\\n \\n <p>OAB symptoms were evaluated using the Overactive Bladder Symptom Score (OABSS).</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>The prevalence of OAB increased with menopausal stage; however, the multivariable-adjusted prevalence ratios for women in menopausal transition and postmenopausal stage were insignificant (<i>p</i><sub>trend</sub> = 0.160) compared to those for premenopausal women. Among individual OAB symptoms, the multivariable-adjusted prevalence ratios for nocturia increased with menopausal stage in a dose–response manner (<i>p</i><sub>trend</sub> = 0.005 for 1 time/day; <i>p</i><sub>trend</sub> < 0.001 for ≥2 times/day). The association between menopausal stages and nocturia occurring ≥2 times/day was evident in women without OAB and with relatively high MENQOL scores, vasomotor symptoms and difficulty sleeping.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusions</h3>\\n \\n <p>The prevalence of OAB, particularly nocturia, increased with menopausal stage, and the association was obvious in women with other menopausal symptoms. This finding underscores the importance of addressing nocturia as a potential menopausal symptom in middle-aged women. Further studies are required to understand the mechanisms linking OAB with menopausal symptoms in middle-aged women.</p>\\n </section>\\n </div>\",\"PeriodicalId\":50729,\"journal\":{\"name\":\"Bjog-An International Journal of Obstetrics and Gynaecology\",\"volume\":\"131 13\",\"pages\":\"1805-1814\"},\"PeriodicalIF\":4.7000,\"publicationDate\":\"2024-07-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bjog-An International Journal of Obstetrics and Gynaecology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/1471-0528.17912\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"OBSTETRICS & GYNECOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bjog-An International Journal of Obstetrics and Gynaecology","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/1471-0528.17912","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
Menopausal stages and overactive bladder symptoms in middle-aged women: A cross-sectional study
Objective
To examine the prevalence of overactive bladder (OAB) according to menopausal stages in middle-aged women.
Design
Cross-sectional study.
Setting
Total Healthcare Center in South Korea.
Population
Middle-aged Korean women (n=3469, mean age, 49.5 ± 2.9 years).
Methods
Menopausal stages were defined according to the Stages of Reproductive Aging Workshop +10 criteria, and menopausal symptoms were assessed using the Korean version of Menopause-Specific Quality of Life (MENQOL). Logistic regression models were used to estimate prevalence ratios with 95% confidence intervals for OAB according to menopausal stage and to assess the associations with menopausal symptoms.
Main Outcome Measures
OAB symptoms were evaluated using the Overactive Bladder Symptom Score (OABSS).
Results
The prevalence of OAB increased with menopausal stage; however, the multivariable-adjusted prevalence ratios for women in menopausal transition and postmenopausal stage were insignificant (ptrend = 0.160) compared to those for premenopausal women. Among individual OAB symptoms, the multivariable-adjusted prevalence ratios for nocturia increased with menopausal stage in a dose–response manner (ptrend = 0.005 for 1 time/day; ptrend < 0.001 for ≥2 times/day). The association between menopausal stages and nocturia occurring ≥2 times/day was evident in women without OAB and with relatively high MENQOL scores, vasomotor symptoms and difficulty sleeping.
Conclusions
The prevalence of OAB, particularly nocturia, increased with menopausal stage, and the association was obvious in women with other menopausal symptoms. This finding underscores the importance of addressing nocturia as a potential menopausal symptom in middle-aged women. Further studies are required to understand the mechanisms linking OAB with menopausal symptoms in middle-aged women.
期刊介绍:
BJOG is an editorially independent publication owned by the Royal College of Obstetricians and Gynaecologists (RCOG). The Journal publishes original, peer-reviewed work in all areas of obstetrics and gynaecology, including contraception, urogynaecology, fertility, oncology and clinical practice. Its aim is to publish the highest quality medical research in women''s health, worldwide.