一名患有精神分裂症的青少年服用帕潘立酮棕榈酸酯后出现的肛门痉挛--非常罕见的锥体外系副作用。

Psychopharmacology bulletin Pub Date : 2024-07-08
Ahmed Naguy, Soliman Al-Khadhari
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引用次数: 0

摘要

作者在此报告了一例有趣的病例:一名被诊断患有精神分裂症的青少年在服用 LAI 帕潘立酮棕榈酸酯后,出现了不同寻常的肌张力障碍反应,表现为肛门失禁,并伪装成便秘和粪便嵌塞。据我们所知,这是有关抗精神病药物诱发肛门失禁的最早报道之一,尤其是在青少年群体中。临床医生应注意可能与使用高能量抗精神病药物有关的不寻常形式的运动障碍。
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Anismus-A Very Unusual Extrapyramidal Side Effect of Paliperidone Palmitate in an Adolescent with Schizo-Affective Disorder.

Here, authors report on an interesting case of an adolescent with a diagnosis of schizo-affective disorder, maintained on LAI paliperidone palmitate that developed an unusual dystonic reaction in form of anismus that masquerade as constipation and faecal impaction. To our knowledge, this is one of the earliest reports of antipsychotic-induced anismus notably in adolescent population. Clinicians should be mindful of unusual forms of dyskinesias that might be associated with high-potency antipsychotic use.

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