从一源多物的角度分析中药生姜的药理活性和临床应用。

IF 5.3 3区 医学 Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE Chinese Medicine Pub Date : 2024-07-12 DOI:10.1186/s13020-024-00969-z
Cheng Zhang, Anyang Rao, Cui Chen, Yuqing Li, Xiuchi Tan, Jiaxin Long, Xinyue Wang, Junjie Cai, Jiquan Huang, Hua Luo, Chuwen Li, Yuanye Dang
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引用次数: 0

摘要

所有类型的生姜都有共同的基本成分,但在功效和药用方面却有不同的优势和倾向。鲜姜能有效促进体内的运动,缓解呕吐、发汗和缓解外感症状。干姜既有防御作用,又有兴奋作用,能有效提高体内温度,增强阳气。鲜姜比干姜更补水,善于温中止痛、止血、止泻。干姜具有温中散寒、温中止泻的功效。干姜在温暖的环境中生长旺盛,并有恢复其温暖特性的趋势。烤姜的含水量不如干姜,但通过温中止痛、止血、止泻,效果显著。通过炭化产生的姜炭和炒炭具有很好的保温性能,在温经止血方面效果显著。烤姜的药效和扩散能力不如鲜姜,含水量也不如干姜。这种物质的药性温和,有利于缓解体弱患者的呕吐症状。它的主要作用模式是中焦。尽管如此,各种中药的主要化学成分因其共同的基本元素而几乎相同。尤其是生姜,具有抗氧化、抗炎、抗肿瘤、抗菌和抗凝血等多种药理作用。然而,现代药理学研究并未充分认识到生姜的临床药用价值,因此无法为临床用药提供准确的指导。这种情况对传统中医药在当代的发展产生了负面影响。生姜现代化研究通过对前景的分析和思考来进行。它以中医理论为基础,结合中医哲学的综合视角。要实现生姜的现代化,必须正确认识 "以效认性、药性同源、性效互显 "和 "合理利用现代药物研究技术 "的理念。运用这些原则,我们就能为生姜的发展架起一座桥梁。
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Pharmacological activity and clinical application analysis of traditional Chinese medicine ginger from the perspective of one source and multiple substances.

All types of ginger have common fundamental components, although they possess distinct strengths and inclinations when it comes to effectiveness and medicinal applications. Fresh ginger possesses the ability to effectively stimulate movement within the body, alleviate the act of vomiting, induce sweating, and provide relief for external syndromes. Dried ginger possesses both defensive and stimulant characteristics, which effectively raise the internal temperature and enhance the Yang energy. Fresh ginger is more hydrating than dried ginger, highly skilled at heating the Middle-jiao, alleviating pain, halting bleeding, and managing diarrhea. Dried ginger possesses the ability to alleviate coldness when consumed in a heated form, as well as to alleviate diarrhea when consumed in a heated form. It thrives in warm conditions and has a tendency to revert back to its warm nature. The moisture content of baked ginger is inferior to that of dried ginger, but it is highly effective in alleviating pain, bleeding, and diarrhea by warming the Middle-jiao. Ginger charcoal and stir-fried charcoal, produced through carbonization, have excellent heat retention properties and are effective in warming meridians and stopping bleeding. The potency and ability to spread of roasted ginger is less intense compared to fresh ginger, and its moisture content is not as low as that of dried ginger. The medicinal characteristics of this substance are gentle, making it beneficial for alleviating vomiting in patients who are physically frail. Its primary mode of action is on the Middle-jiao. Nevertheless, the main chemical compositions of various traditional Chinese medicines are nearly identical due to their shared base element. Ginger, in particular, possesses a range of pharmacological activities including antioxidant, anti-inflammatory, anti-tumor, anti-bacterial, and anticoagulant properties. However, modern pharmacological research has not fully acknowledged the clinical medicinal value of ginger and consequently, fails to provide accurate guidance for clinical medication. This situation has a negative impact on the contemporary advancement of traditional Chinese medicine (TCM). The research on modernizing ginger is conducted by analyzing and considering the prospects. It is based on Traditional Chinese Medicine (TCM) theory and incorporates the comprehensive perspective of TCM philosophy. In order to modernize ginger, it is essential to have a proper knowledge of the concepts of "recognizing nature by efficacy, homology, and mutual expression of nature and efficacy" and "rationally utilizing modern drug research technology". By applying these principles, we can construct a bridge towards the advancement of ginger.

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来源期刊
Chinese Medicine
Chinese Medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-PHARMACOLOGY & PHARMACY
CiteScore
7.90
自引率
4.10%
发文量
133
审稿时长
31 weeks
期刊介绍: Chinese Medicine is an open access, online journal publishing evidence-based, scientifically justified, and ethical research into all aspects of Chinese medicine. Areas of interest include recent advances in herbal medicine, clinical nutrition, clinical diagnosis, acupuncture, pharmaceutics, biomedical sciences, epidemiology, education, informatics, sociology, and psychology that are relevant and significant to Chinese medicine. Examples of research approaches include biomedical experimentation, high-throughput technology, clinical trials, systematic reviews, meta-analysis, sampled surveys, simulation, data curation, statistics, omics, translational medicine, and integrative methodologies. Chinese Medicine is a credible channel to communicate unbiased scientific data, information, and knowledge in Chinese medicine among researchers, clinicians, academics, and students in Chinese medicine and other scientific disciplines of medicine.
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