早发性帕金森病未满足的需求:脑深部刺激与妊娠。

IF 4 3区 医学 Q2 NEUROSCIENCES Journal of Parkinson's disease Pub Date : 2024-01-01 DOI:10.3233/JPD-240088
Katarzyna Smilowska, Raja Mehanna, Jori E Fleisher, Roy N Alcalay, Kishore Raj Kumar, Connie Marras, Annelien M Oosterbaan, Bart Post, Owen A Ross, Maria Elisa Pimentel Piemonte, Valerie Fraix, Elena Moro, Eng King Tan, Rodolfo Savica
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引用次数: 0

摘要

鉴于母亲年龄不断增长的趋势,早发性帕金森病(PD)女性患者怀孕的频率可能会更高,从而导致生育年龄与帕金森病风险之间的重叠时间更长。如今,在帕金森病的早期阶段,当女性还未绝经时,就可以对帕金森病患者进行脑深部刺激(DBS)治疗。然而,有关 DBS 在孕期安全性的数据却很少。根据对现有文献的回顾,迄今为止仅有一篇文章发表了这一主题。因此,我们就 PD 患者妊娠期使用 DBS 的安全性达成了临床共识。
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Unmet Need in Early-Onset Parkinson's Disease: Deep Brain Stimulation and Pregnancy.

Pregnancy in women with early-onset Parkinson's disease (PD) is likely to have a higher frequency given the trend toward increasing maternal age, thus resulting in a greater overlap time between childbearing age and PD risk. Deep brain stimulation (DBS) therapy is nowadays offered to PD patients at earlier stage of the disease, when women can still be pre-menopausal. However, few data are available about DBS safety during pregnancy. From a review of the available literature, only one article was published on this topic so far. Therefore, we have developed a clinical consensus on the safety of DBS during pregnancy in PD patients.

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来源期刊
CiteScore
8.40
自引率
5.80%
发文量
338
审稿时长
>12 weeks
期刊介绍: The Journal of Parkinson''s Disease (JPD) publishes original research in basic science, translational research and clinical medicine in Parkinson’s disease in cooperation with the Journal of Alzheimer''s Disease. It features a first class Editorial Board and provides rigorous peer review and rapid online publication.
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