阿达木单抗治疗后出现的矛盾性角膜炎和皮炎。

IF 1.2 4区医学 Q3 OPHTHALMOLOGY Journal of Aapos Pub Date : 2024-10-01 DOI:10.1016/j.jaapos.2024.103970

Noor Ghali MS , Arif O. Khan MD

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引用次数: 0

摘要

抗肿瘤坏死因子（TNF）单克隆抗体是治疗风湿病的重要工具。然而，使用这种抗体可能会诱发矛盾性炎症。本病例报告描述了一名6岁女孩在接受阿达木单抗治疗慢性复发性多灶性骨髓炎后出现角膜炎和皮炎的情况。在开始使用外用类固醇并停用阿达木单抗后，角膜炎和皮炎均已消退。

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Paradoxical keratitis and dermatitis following adalimumab treatment

Anti-tumor necrosis factor monoclonal antibodies are an important tool in the management of rheumatologic disease. However, paradoxical inflammation can be precipitated by their use. This case report describes the development of keratitis and dermatitis following adalimumab treatment for chronic recurrent multifocal osteomyelitis in a 6-year-old girl. The keratitis and dermatitis subsided once topical steroids were started and the adalimumab was held.

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来源期刊

Journal of Aapos 医学-小儿科

CiteScore

2.40

自引率

12.50%

发文量

159

审稿时长

55 days

期刊介绍： Journal of AAPOS presents expert information on children''s eye diseases and on strabismus as it affects all age groups. Major articles by leading experts in the field cover clinical and investigative studies, treatments, case reports, surgical techniques, descriptions of instrumentation, current concept reviews, and new diagnostic techniques. The Journal is the official publication of the American Association for Pediatric Ophthalmology and Strabismus.