利用脉冲场消融术对有症状心房颤动和植入 Watchman 装置的患者进行肺静脉隔离的安全性和可行性。

IF 2.1 4区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Journal of Interventional Cardiac Electrophysiology Pub Date : 2024-11-01 Epub Date: 2024-07-15 DOI:10.1007/s10840-024-01876-x

Ivana Garza, Haider Al Taii, Arun Narayanan, Hani Jneid, Dean Sabayon

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引用次数: 0

摘要

背景：脉冲场消融术（PFA）是一种治疗心房颤动（AF）的新型非热心脏消融方法。目前尚未对其在已使用 Watchman 设备的患者身上的应用进行研究：方法：对 7 名有症状房颤并植入 Watchman 设备的患者进行了利用 PFA 的肺静脉隔离 (PVI)。所有病例均在一家学术中心进行：所有病例均在消融术前中位时间 534 天（IQR 365 天）成功为植入 Watchman 装置的患者进行了 PVI。未观察到重大不良事件（术中 CVA、术后 CVA、重大或轻微出血事件、装置栓塞或心脏填塞）。7例患者中有6例在PFA术后使用了低剂量直接口服抗凝剂（DOAC）：我们首次报道了植入 Watchman 装置的房颤患者的 PFA 病例系列。本研究强调了 FARAPULSE PFA 系统在此类患者中的安全性和可行性。

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Safety and feasibility of pulmonary vein isolation utilizing pulsed field ablation in patients with symptomatic atrial fibrillation and implanted Watchman devices.

Background: Pulsed field ablation (PFA) is a novel method of non-thermal cardiac ablation for atrial fibrillation (AF). Its use on patients with pre-existing Watchman devices has not been studied.

Methods: Pulmonary vein isolation (PVI) utilizing PFA was performed in 7 patients with symptomatic AF and implanted Watchman devices. All cases were conducted at a single academic center.

Results: Successful PVI in patients with Watchman devices implanted at a median time of 534 days prior to the index ablation procedure (IQR 365 days) was achieved in all cases. No major adverse events (intraprocedural CVA, post-procedural CVA, major or minor bleeding events, device embolization, or cardiac tamponade) were observed. In 6 of 7 patients, a low-dose direct oral anticoagulant (DOAC) strategy was implemented post-PFA.

Conclusion: We present the first reported case series of PFA in patients with AF and implanted Watchman devices. This study highlights the safety and feasibility of the FARAPULSE PFA system in this patient population.

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来源期刊

Journal of Interventional Cardiac Electrophysiology 医学-心血管系统

CiteScore

4.30

自引率

11.10%

发文量

320

审稿时长

4-8 weeks

期刊介绍： The Journal of Interventional Cardiac Electrophysiology is an international publication devoted to fostering research in and development of interventional techniques and therapies for the management of cardiac arrhythmias. It is designed primarily to present original research studies and scholarly scientific reviews of basic and applied science and clinical research in this field. The Journal will adopt a multidisciplinary approach to link physical, experimental, and clinical sciences as applied to the development of and practice in interventional electrophysiology. The Journal will examine techniques ranging from molecular, chemical and pharmacologic therapies to device and ablation technology. Accordingly, original research in clinical, epidemiologic and basic science arenas will be considered for publication. Applied engineering or physical science studies pertaining to interventional electrophysiology will be encouraged. The Journal is committed to providing comprehensive and detailed treatment of major interventional therapies and innovative techniques in a structured and clinically relevant manner. It is directed at clinical practitioners and investigators in the rapidly growing field of interventional electrophysiology. The editorial staff and board reflect this bias and include noted international experts in this area with a wealth of expertise in basic and clinical investigation. Peer review of all submissions, conflict of interest guidelines and periodic editorial board review of all Journal policies have been established.