英国的盘尾丝虫感染:对已发表病例的系统回顾和荟萃分析。

IF 3.6 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Clinical Medicine Pub Date : 2024-07-01 Epub Date: 2024-07-14 DOI:10.1016/j.clinme.2024.100227
Ali M Alam, Cansu Ozdemir, Nada Reza
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引用次数: 0

摘要

强直性脊柱炎是一种蠕虫感染,症状各不相同,无症状表现也很常见。在免疫力低下的状态下,慢性强直性脊柱炎可导致高死亡率的 "高感染"。了解高危人群和症状可以指导筛查和早期治疗,从而降低高感染风险。对描述英国强直性脊柱炎患者的研究进行了系统回顾,共汇总了 1308 名患者。无症状病例的加权汇总患病率(WPP)为27.7%(95%CI 17.1-39.5%,I2=92%,P2=93%,P2=99%,P2=70%,P=0.03)。症状随队列特征而变化。虽然无症状表现很常见,但患者也可能出现腹痛、腹泻或皮疹。对高危人群中无症状者的筛查阈值要低。
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Strongyloides stercoralis infection in the UK: A systematic review and meta-analysis of published cases.

Strongyloidiasis is a helminth infection where symptoms vary, and asymptomatic presentation is common. Chronic strongyloidiasis can cause a high mortality 'hyper-infection' in immunocompromised states. Understanding at risk populations and symptomology can guide screening and early treatment to reduce hyper-infection risk. A systematic review of studies describing patients in the UK with strongyloidiasis pooled a total of 1,308 patients. Weighted pooled prevalence (WPP) of asymptomatic cases was 27.7% (95% CI 17.1-39.5%, I2 = 92%, p < 0.01). At-risk populations included migrants, returning travellers and armed forces personnel. The most common symptoms reported were abdominal pain (WPP 32.1% (95% CI 20.5-44.8%), I2 = 93%, p < 0.01), rashes (WPP 38.4% (95% CI 13.1-67.7%), I2 = 99%, p < 0.01) and diarrhoea (WPP 12.6% (95% CI 6.7-19.9%), I2=70%, p = 0.03). Symptomatology varied with cohort characteristics. Although asymptomatic presentation is common, patients may present with abdominal pain, diarrhoea or rashes. A low threshold for screening symptomatic individuals in at-risk groups is required.

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来源期刊
Clinical Medicine
Clinical Medicine 医学-医学:内科
CiteScore
7.20
自引率
0.00%
发文量
0
审稿时长
6-12 weeks
期刊介绍: Clinical Medicine is aimed at practising physicians in the UK and overseas and has relevance to all those managing or working within the healthcare sector. Available in print and online, the journal seeks to encourage high standards of medical care by promoting good clinical practice through original research, review and comment. The journal also includes a dedicated continuing medical education (CME) section in each issue. This presents the latest advances in a chosen specialty, with self-assessment questions at the end of each topic enabling CPD accreditation to be acquired. ISSN: 1470-2118 E-ISSN: 1473-4893 Frequency: 6 issues per year
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