床旁内窥镜清洁过程中气溶胶产生和传播的潜在影响。

IF 4.7 3区 生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Journal of Zhejiang University SCIENCE B Pub Date : 2024-07-15 DOI:10.1631/jzus.B2300552
Tingting Sheng, Xin Wu, Li Cen, Ye Lu, Chenying Zhou, Qing Gu
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引用次数: 0

摘要

空气传播是最常见的院内感染类型之一。近年来,空气传播疾病频频爆发,如 2002 年的严重急性呼吸系统综合征(SARS)、2012 年的中东呼吸系统综合征(MERS)和 2019 年冠状病毒病(COVID-19),后者自 2019 年底开始肆虐,使气溶胶对健康的影响再次成为人们关注的焦点(Gralton 等人,2011 年;Wang 等人,2021 年)。越来越多的研究表明,某些传染性极强的病原体可以保持长期稳定,并通过气溶胶有效传播(Leung,2021;Lv 等人,2021)。如前所述,与不能通过气溶胶有效传播的病毒相比,能通过气溶胶有效传播的流感病毒能保持更长时间的稳定。世界卫生组织(WHO)指出,气溶胶产生程序(AGPs)在医院气溶胶传播中扮演着重要角色(Calderwood 等人,2021 年)。AGP 指的是产生气溶胶的医疗程序,包括牙科程序、气管插管、吸痰和腹腔镜手术,据报道,AGP 与医务人员的鼻腔感染风险增加密切相关(Hamilton,2021 年)。
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Potential effects of aerosol generation and transmission during bedside endoscope cleaning.

Airborne transmission is among the most frequent types of nosocomial infection. Recent years have witnessed frequent outbreaks of airborne diseases, such as severe acute respiratory syndrome (SARS) in 2002, Middle East respiratory syndrome (MERS) in 2012, and coronavirus disease 2019 (COVID-19), with the latter being on the rampage since the end of 2019 and bringing the effect of aerosols on health back to the fore (Gralton et al., 2011; Wang et al., 2021). An increasing number of studies have shown that certain highly transmissible pathogens can maintain long-term stability and efficiently spread through aerosols (Leung, 2021; Lv et al., 2021). As reported previously, influenza viruses that can spread efficiently through aerosols remain stable for a longer period compared to those that cannot. The World Health Organization (WHO) has stated that aerosol-generating procedures (AGPs) play an important role in aerosol transmission in hospitals (Calderwood et al., 2021). AGPs, referring to medical procedures that produce aerosols, including dental procedures, endotracheal intubation, sputum aspiration, and laparoscopic surgeries, have been reported to be significantly associated with an increased risk of nosocomial infection among medical personnel (Hamilton, 2021).

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来源期刊
Journal of Zhejiang University SCIENCE B
Journal of Zhejiang University SCIENCE B 生物-生化与分子生物学
CiteScore
8.70
自引率
13.70%
发文量
2125
审稿时长
3.0 months
期刊介绍: Journal of Zheijang University SCIENCE B - Biomedicine & Biotechnology is an international journal that aims to present the latest development and achievements in scientific research in China and abroad to the world’s scientific community. JZUS-B covers research in Biomedicine and Biotechnology and Biochemistry and topics related to life science subjects, such as Plant and Animal Sciences, Environment and Resource etc.
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