经支气管冷冻消融术作为中央气道恶性肿瘤的局部治疗方法。

IF 3.5 3区医学 Q2 RESPIRATORY SYSTEM Respiration Pub Date : 2024-01-01 Epub Date: 2024-07-22 DOI:10.1159/000540299

Masamitsu Hamakawa, Takashi Niwa, Yasushi Fukuda, Toshihide Yokoyama, Tadashi Ishida

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引用次数: 0

摘要

导读经支气管冷冻消融术可用于外周气道恶性肿瘤，但不适用于中央气道恶性肿瘤。我们在两名患有中央气道病变的患者身上展示了经支气管低温消融术：病例 1 是一名 86 岁的妇女，因肺部腺癌术后复发而出现气管内转移。患者使用高频电外科套管和三次经支气管低温消融术切除了肿瘤。第三次手术后的五个月内气管没有复发。病例 2 是一名 83 岁的男性，因肺鳞状细胞癌术后复发而出现中间支气管转移。他使用高频电外科套管和一次经支气管冷冻消融术切除了肿瘤。治疗后 12 个月，中间支气管内的肿瘤没有复发。两个病例中唯一的不良反应是轻微出血：结论：经支气管冷冻消融术值得考虑作为中央气道恶性肿瘤的局部治疗方法。

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Transbronchial Cryoablation as Local Treatment for Central Airway Malignant Tumor.

Introduction: Transbronchial cryoablation has been performed for peripheral but not central airway malignant tumor. We demonstrate transbronchial cryoablation in 2 patients with central airway lesions.

Case presentation: Case 1 was an 86-year-old woman who developed intratracheal metastasis associated with postoperative recurrence of lung adenocarcinoma. The tumor was resected using a high-frequency electrosurgical snare and three transbronchial cryoablations. There was no tracheal recurrence in the 5 months after the third procedure. Case 2 was an 83-year-old man who developed intermediate bronchial metastasis associated with postoperative recurrence of lung squamous cell carcinoma. The tumor was resected using a high-frequency electrosurgical snare and one transbronchial cryoablation. There was no tumor recurrence in the bronchus intermedius for 12 months after treatment. In both cases, the only adverse event was minor bleeding.

Conclusion: Transbronchial cryoablation deserves consideration as local treatment for central airway malignant tumors.

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来源期刊

Respiration 医学-呼吸系统

CiteScore

7.30

自引率

5.40%

发文量

审稿时长

4-8 weeks

期刊介绍： ''Respiration'' brings together the results of both clinical and experimental investigations on all aspects of the respiratory system in health and disease. Clinical improvements in the diagnosis and treatment of chest and lung diseases are covered, as are the latest findings in physiology, biochemistry, pathology, immunology and pharmacology. The journal includes classic features such as editorials that accompany original articles in clinical and basic science research, reviews and letters to the editor. Further sections are: Technical Notes, The Eye Catcher, What’s Your Diagnosis?, The Opinion Corner, New Drugs in Respiratory Medicine, New Insights from Clinical Practice and Guidelines. ''Respiration'' is the official journal of the Swiss Society for Pneumology (SGP) and also home to the European Association for Bronchology and Interventional Pulmonology (EABIP), which occupies a dedicated section on Interventional Pulmonology in the journal. This modern mix of different features and a stringent peer-review process by a dedicated editorial board make ''Respiration'' a complete guide to progress in thoracic medicine.