机器人辅助前列腺癌根治术患者术后长期尿失禁的临床特征和预测因素:倾向匹配分析

IF 1.8 3区 医学 Q3 UROLOGY & NEPHROLOGY International Journal of Urology Pub Date : 2024-10-01 Epub Date: 2024-07-17 DOI:10.1111/iju.15533
Yuki Kohada, Hiroyuki Kitano, Ryo Tasaka, Shunsuke Miyamoto, Tomoya Hatayama, Hiroyuki Shikuma, Kyohsuke Iwane, Kazuma Yukihiro, Kenshiro Takemoto, Miki Naito, Kohei Kobatake, Yohei Sekino, Keisuke Goto, Akihiro Goriki, Keisuke Hieda, Nobuyuki Hinata
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引用次数: 0

摘要

研究目的本研究旨在阐明机器人辅助前列腺癌根治术(RARP)术后长期尿失禁(PUI)的临床特征和预测因素:本研究纳入了在我院接受前列腺癌根治术(RARP)的患者,并在RARP术后60个月时将其分为PUI组(尿垫≥1片/天)和尿失禁组(尿垫0片/天)。为了匹配这两组患者的术前排尿状况,我们对他们进行了倾向得分匹配分析,并采用了多种术前排尿状况(前列腺癌扩展指数综合排尿亚域、国际前列腺症状总评分(IPSS)和 IPSS-生活质量评分)。比较术前和 RARP 术后 60 个月前排尿状况和治疗满意度的连续变化,并使用多变量逻辑回归分析评估长期 PUI 的预测因素:共有 228 名患者被纳入 PUI 组和尿失禁组(各 114 人)。虽然两组患者术前排尿状况无明显差异,但 PUI 组患者术后排尿状况总体上明显差于失禁组。从术后 12 个月到 60 个月,PUI 组的治疗满意度也明显低于失禁组。多变量逻辑回归分析表明,年龄(≥70 岁)和生化复发(BCR)是长期 PUI 组的重要预测因素(P 结论:长期 PUI 组患者的总体情况较差:与尿失禁组相比,长期 PUI 患者的术后总体排尿状况较差,治疗满意度较低。在实施 RARP 时,考虑年龄和 BCR 风险对于预测长期 PUI 非常重要。
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Clinical characteristics and predictors of long-term postoperative urinary incontinence in patients treated with robot-assisted radical prostatectomy: A propensity-matched analysis.

Objectives: This study aimed to elucidate the clinical characteristics and predictors of long-term postoperative urinary incontinence (PUI) after robot-assisted radical prostatectomy (RARP).

Methods: This study included patients who underwent RARP at our institution and were stratified into PUI (≥1 pad/day) and continence (0 pad/day) groups at 60 months after RARP. A propensity score-matched analysis with multiple preoperative urinary status (Expanded Prostate Cancer Index Composite urinary subdomains, total International Prostate Symptom Score (IPSS), and IPSS-quality of life scores) was performed to match preoperative urinary status in these groups. Serial changes in urinary status and treatment satisfaction preoperatively and until 60 months after RARP were compared, and predictors of long-term PUI were assessed using multivariate logistic regression analysis.

Results: A total of 228 patients were included in the PUI and continence groups (114 patients each). Although no significant difference in preoperative urinary status was observed between the two groups, the postoperative urinary status significantly worsened overall in the PUI group than in the continence group. Treatment satisfaction was also significantly lower in the PUI group than in the continence group from 12 to 60 months postoperatively. Multivariate logistic regression analysis revealed that age (≥70 years) and biochemical recurrence (BCR) were significant predictors of the long-term PUI group (p < 0.05).

Conclusions: Patients with long-term PUI had poor overall postoperative urinary status and lower treatment satisfaction than the continence group. Considering the age and risk of BCR is important for predicting long-term PUI when performing RARP.

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来源期刊
International Journal of Urology
International Journal of Urology 医学-泌尿学与肾脏学
CiteScore
4.70
自引率
11.50%
发文量
340
审稿时长
3 months
期刊介绍: International Journal of Urology is the official English language journal of the Japanese Urological Association, publishing articles of scientific excellence in urology. Submissions of papers from all countries are considered for publication. All manuscripts are subject to peer review and are judged on the basis of their contribution of original data and ideas or interpretation.
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