基于共生素的营养教育干预对精神分裂症谱系障碍的精神病理学和心脏代谢疗效。双臂随机临床试验

IF 2.5 4区 医学 Q2 PSYCHIATRY European Journal of Psychiatry Pub Date : 2024-07-16 DOI:10.1016/j.ejpsy.2024.100262
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引用次数: 0

摘要

背景和目的知识的进步有助于全面了解营养模式对精神健康的影响。方法 对 50 名被诊断为精神分裂症谱系障碍的患者进行了随机临床试验(双臂、双盲、平衡阻断、为期 6 个月的干预)。对照组单独接受常规饮食建议。干预组则接受强化饮食建议,即增加食用共生成分高的食物(发酵食品、全谷物、绿叶蔬菜和膳食纤维含量高的水果等)。研究人员收集了基线、三个月和六个月的心血管和精神病理状态数据。此外,每月还对人体测量参数进行分析。与对照组相比,干预组的 PANSS-GP 分量表和 PSP 量表评分在 3-6 个月内有所改善(p < 0.05)。所有变量的人体测量值均有所下降(p < 0.05)。结论通过营养教育增加高共生成分食物的摄入量,对精神分裂症谱系障碍患者的心血管代谢和精神病理特征产生了积极影响。此外,高级心理健康护士在开展营养教育和促进这些患者的健康生活方式方面也发挥了重要作用。
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Psychopathological and cardiometabolic efficacy of a nutritional education intervention based on symbiotics in schizophrenia spectrum disorders. Two-arm Randomised Clinical Trial

Background and objectives

Advances in knowledge have contributed to the global understanding of nutritional patterns' influence on mental health. The aim was to determine the impact of a high-symbiotic diet on cardio-metabolic and psychopathological outcomes in schizophrenia.

Methods

A randomised clinical trial (two-arm, double-blind, balanced-block, six-month intervention) was conducted on 50 individuals diagnosed with schizophrenia spectrum disorder. The control group received conventional dietary advice individually. The intervention group received intensive dietary advice based on the increasing consumption of food with high symbiotic content (fermented foods, whole grains, green leafy vegetables and fruits high in dietary fibre, among others). Researchers collected data on cardiovascular and psychopathological status at baseline, three and six months. In addition, anthropometric parameters were analysed monthly.

Results

Forty-four subjects were analysed. Compared to the control group, the intervention group demonstrated improvements in the PANSS-GP subscale and the PSP scale scores over 3–6 months (p < 0.05). Anthropometric values were decreased in all the variables (p < 0.05). Systolic blood pressure decreased between 3 and 6 months (p = 0.049).

Conclusions

Nutrition education for increasing the consumption of foods with high symbiotic content has positively impacted the cardio-metabolic and psychopathological profile in patients with schizophrenia spectrum disorders. In addition, advanced practice mental health nurses have been shown to play a prominent role in developing nutrition education and promoting healthy lifestyles in these patients.

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来源期刊
CiteScore
2.90
自引率
0.00%
发文量
40
审稿时长
43 days
期刊介绍: The European journal of psychiatry is a quarterly publication founded in 1986 and directed by Professor Seva until his death in 2004. It was originally intended to report “the scientific activity of European psychiatrists” and “to bring about a greater degree of communication” among them. However, “since scientific knowledge has no geographical or cultural boundaries, is open to contributions from all over the world”. These principles are maintained in the new stage of the journal, now expanded with the help of an American editor.
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