发展公私研发联盟,加快阿尔茨海默病药物的开发。

IF 6.5 2区 医学 Q1 PHARMACOLOGY & PHARMACY Drug Discovery Today Pub Date : 2024-07-15 DOI:10.1016/j.drudis.2024.104103
Joel West , Paul Olk
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引用次数: 0

摘要

为加快阿尔茨海默病(AD)药物的开发,开放科学、公私研发联合体的建立起到了推动作用。研发联盟提供了一个更好的结构,在一系列组织之间产生和传播阿兹海默症知识,同时还能协调他们的利益。通过对 46 个完全或部分专注于反兴奋剂的公私研发联盟的档案和访谈数据的收集,我们发现了两个重要的创新点:一是创建了新的联盟类型,以促进单个联盟之外的协调;二是组织加入多个联盟的做法。总体而言,这些创新为成员组织提供了不同的途径来推进注意力缺失症研究。这些发现对成员组织如何在注意力缺失症药物开发过程中开展合作具有重要意义。
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Developing public–private R&D consortia to accelerate Alzheimer’s disease drug development

Efforts to accelerate Alzheimer’s disease (AD) drug development have been spurred on by the creation of open science, public–private R&D consortia. An R&D consortium provides an improved structure for generating and disseminating AD knowledge across a range of organizations while also aligning their interests. Drawing from archival and interview data collected on 46 public–private R&D consortia focused wholly or in part on AD, we uncover two important innovations: the creation of novel consortium types that facilitate coordination beyond the individual consortium, and the practice of organizations joining multiple consortia. Collectively these innovations provide member organizations with different pathways for advancing AD research. These findings have significant implications for how member organizations should approach collaboration in the AD drug development process.

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来源期刊
Drug Discovery Today
Drug Discovery Today 医学-药学
CiteScore
14.80
自引率
2.70%
发文量
293
审稿时长
6 months
期刊介绍: Drug Discovery Today delivers informed and highly current reviews for the discovery community. The magazine addresses not only the rapid scientific developments in drug discovery associated technologies but also the management, commercial and regulatory issues that increasingly play a part in how R&D is planned, structured and executed. Features include comment by international experts, news and analysis of important developments, reviews of key scientific and strategic issues, overviews of recent progress in specific therapeutic areas and conference reports.
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