非囊性纤维化引起的支气管扩张症

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引用次数: 0

摘要

支气管扩张症是一种临床放射学疾病,由气道炎症和感染导致的不可逆支气管扩张引起呼吸道症状,通常是有痰咳嗽和感染性加重。支气管扩张症有多种病因,包括肺内和肺外病因,其临床表现多种多样。虽然高达 35%-50% 的严重慢性阻塞性肺病患者和 25% 的严重哮喘患者会出现支气管扩张,但其发病率仍不清楚,因此诊断率明显偏低。慢性支气管细菌感染很常见,铜绿假单胞菌是导致预后较差的病原体。支气管扩张症的治疗有三个基本特征:必须是多学科的(多个专科参与)、金字塔式的(从初级保健到最专业的单位)和多维度的(对构成疾病的所有方面进行管理)。
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Bronchiectasis not due to cystic fibrosis

Bronchiectasis is a clinical-radiological condition composed of irreversible bronchial dilation due to inflammation and infection of the airways, which causes respiratory symptoms, usually productive cough and infectious exacerbations. Bronchiectasis can have multiple causes, both pulmonary and extrapulmonary, and its clinical presentation is very heterogenous. Its prevalence is unknown, although up to 35%–50% of severe COPD and 25% of severe asthma present them, so their underdiagnosis is evident. Chronic bacterial bronchial infection is common, and Pseudomonas aeruginosa is the pathogen that has been found to imply a worse prognosis. Treatment of bronchiectasis has three fundamental characteristics: it must be multidisciplinary (involvement of several specialties), pyramidal (from primary care to the most specialized units) and multidimensional (management of all aspects that make up the disease).

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