{"title":"牲畜是伊朗西南部人畜共患病布拉氏囊虫亚型的适当储库:对公共卫生的潜在威胁","authors":"","doi":"10.1016/j.genrep.2024.101975","DOIUrl":null,"url":null,"abstract":"<div><p><em>Blastocystis</em> sp. is a protozoan parasite commonly found in the gastrointestinal tract of humans and various animals, including livestock. This study aimed to assess the prevalence, subtypes (STs) distribution, and zoonotic transmission potential of <em>Blastocystis</em> sp. in livestock in southwestern Iran. A cross-sectional study was conducted, and fecal samples were collected from cattle and sheep in Shiraz, the capital city of Fars province. Molecular analysis was conducted to amplify a specific fragment from the SSU rRNA gene through PCR and sequencing to detect <em>Blastocystis</em>.sp. and identify the related STs in the livestock population. This study identified a relatively low occurrence of <em>Blastocystis</em> sp. in cattle (8 %; 4/50) and sheep (6 %; 3/50). Nonetheless, different zoonotic STs were found in these animals. In cattle, ST10 accounted for 50 % (2/4), ST1 for 25 % (1/4), and ST3 for 25 % (1/4) of the cases. In sheep, 66.7 % (2/3) and 33.3 % (1/3) of the positive isolates were classified as ST10 and ST3, respectively. <em>Blastocystis</em> sp. was more common in young animals and females, as well as in diarrheal samples (P > 0.05). The findings suggest a significant risk of zoonotic transmission of <em>Blastocystis</em> sp. from livestock to humans in the region. Although this small-scale research was not suitable for firm epidemiological conclusions, it underscores the importance of monitoring and implementing control measures to prevent zoonotic transmission of <em>Blastocystis</em> sp. from livestock to humans in southwestern Iran, highlighting the need for further research to better understand the epidemiology and public health implications of this parasite.</p></div>","PeriodicalId":12673,"journal":{"name":"Gene Reports","volume":null,"pages":null},"PeriodicalIF":1.0000,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Livestock as proper reservoirs for zoonotic Blastocystis subtypes in southwestern Iran: A potential threat to public health\",\"authors\":\"\",\"doi\":\"10.1016/j.genrep.2024.101975\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p><em>Blastocystis</em> sp. is a protozoan parasite commonly found in the gastrointestinal tract of humans and various animals, including livestock. This study aimed to assess the prevalence, subtypes (STs) distribution, and zoonotic transmission potential of <em>Blastocystis</em> sp. in livestock in southwestern Iran. A cross-sectional study was conducted, and fecal samples were collected from cattle and sheep in Shiraz, the capital city of Fars province. Molecular analysis was conducted to amplify a specific fragment from the SSU rRNA gene through PCR and sequencing to detect <em>Blastocystis</em>.sp. and identify the related STs in the livestock population. This study identified a relatively low occurrence of <em>Blastocystis</em> sp. in cattle (8 %; 4/50) and sheep (6 %; 3/50). Nonetheless, different zoonotic STs were found in these animals. In cattle, ST10 accounted for 50 % (2/4), ST1 for 25 % (1/4), and ST3 for 25 % (1/4) of the cases. In sheep, 66.7 % (2/3) and 33.3 % (1/3) of the positive isolates were classified as ST10 and ST3, respectively. <em>Blastocystis</em> sp. was more common in young animals and females, as well as in diarrheal samples (P > 0.05). The findings suggest a significant risk of zoonotic transmission of <em>Blastocystis</em> sp. from livestock to humans in the region. Although this small-scale research was not suitable for firm epidemiological conclusions, it underscores the importance of monitoring and implementing control measures to prevent zoonotic transmission of <em>Blastocystis</em> sp. from livestock to humans in southwestern Iran, highlighting the need for further research to better understand the epidemiology and public health implications of this parasite.</p></div>\",\"PeriodicalId\":12673,\"journal\":{\"name\":\"Gene Reports\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2024-07-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Gene Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2452014424000980\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"GENETICS & HEREDITY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Gene Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2452014424000980","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"GENETICS & HEREDITY","Score":null,"Total":0}
Livestock as proper reservoirs for zoonotic Blastocystis subtypes in southwestern Iran: A potential threat to public health
Blastocystis sp. is a protozoan parasite commonly found in the gastrointestinal tract of humans and various animals, including livestock. This study aimed to assess the prevalence, subtypes (STs) distribution, and zoonotic transmission potential of Blastocystis sp. in livestock in southwestern Iran. A cross-sectional study was conducted, and fecal samples were collected from cattle and sheep in Shiraz, the capital city of Fars province. Molecular analysis was conducted to amplify a specific fragment from the SSU rRNA gene through PCR and sequencing to detect Blastocystis.sp. and identify the related STs in the livestock population. This study identified a relatively low occurrence of Blastocystis sp. in cattle (8 %; 4/50) and sheep (6 %; 3/50). Nonetheless, different zoonotic STs were found in these animals. In cattle, ST10 accounted for 50 % (2/4), ST1 for 25 % (1/4), and ST3 for 25 % (1/4) of the cases. In sheep, 66.7 % (2/3) and 33.3 % (1/3) of the positive isolates were classified as ST10 and ST3, respectively. Blastocystis sp. was more common in young animals and females, as well as in diarrheal samples (P > 0.05). The findings suggest a significant risk of zoonotic transmission of Blastocystis sp. from livestock to humans in the region. Although this small-scale research was not suitable for firm epidemiological conclusions, it underscores the importance of monitoring and implementing control measures to prevent zoonotic transmission of Blastocystis sp. from livestock to humans in southwestern Iran, highlighting the need for further research to better understand the epidemiology and public health implications of this parasite.
Gene ReportsBiochemistry, Genetics and Molecular Biology-Genetics
CiteScore
3.30
自引率
7.70%
发文量
246
审稿时长
49 days
期刊介绍:
Gene Reports publishes papers that focus on the regulation, expression, function and evolution of genes in all biological contexts, including all prokaryotic and eukaryotic organisms, as well as viruses. Gene Reports strives to be a very diverse journal and topics in all fields will be considered for publication. Although not limited to the following, some general topics include: DNA Organization, Replication & Evolution -Focus on genomic DNA (chromosomal organization, comparative genomics, DNA replication, DNA repair, mobile DNA, mitochondrial DNA, chloroplast DNA). Expression & Function - Focus on functional RNAs (microRNAs, tRNAs, rRNAs, mRNA splicing, alternative polyadenylation) Regulation - Focus on processes that mediate gene-read out (epigenetics, chromatin, histone code, transcription, translation, protein degradation). Cell Signaling - Focus on mechanisms that control information flow into the nucleus to control gene expression (kinase and phosphatase pathways controlled by extra-cellular ligands, Wnt, Notch, TGFbeta/BMPs, FGFs, IGFs etc.) Profiling of gene expression and genetic variation - Focus on high throughput approaches (e.g., DeepSeq, ChIP-Seq, Affymetrix microarrays, proteomics) that define gene regulatory circuitry, molecular pathways and protein/protein networks. Genetics - Focus on development in model organisms (e.g., mouse, frog, fruit fly, worm), human genetic variation, population genetics, as well as agricultural and veterinary genetics. Molecular Pathology & Regenerative Medicine - Focus on the deregulation of molecular processes in human diseases and mechanisms supporting regeneration of tissues through pluripotent or multipotent stem cells.