估计顺式和反式对基因调控差异的贡献

bioRxiv Pub Date : 2024-07-16 DOI:10.1101/2024.07.13.603403
Ingileif B. Hallgrímsdóttir, M. Carilli, L. Pachter
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引用次数: 0

摘要

我们描述了一个坐标系和相关的假设检验框架,用于确定两个同源品系或物种之间的基因表达差异是由顺式调控还是反式调控造成的。
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Estimating cis and trans contributions to differences in gene regulation
We describe a coordinate system and associated hypothesis testing framework for determining whether cis or trans regulation is responsible for differences in gene expression between two homozygous strains or species.
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