Manal Taimah, Amar Ahmad, Mohammad Al-Houqani, Abdullah Al Junaibi, Youssef Idaghdour, A. Abdulle, Raghib Ali
{"title":"阿联酋成年人中阻塞性睡眠呼吸暂停风险与 2 型糖尿病之间的关系:阿联酋健康未来研究的结果","authors":"Manal Taimah, Amar Ahmad, Mohammad Al-Houqani, Abdullah Al Junaibi, Youssef Idaghdour, A. Abdulle, Raghib Ali","doi":"10.3389/fendo.2024.1395886","DOIUrl":null,"url":null,"abstract":"Obstructive sleep apnea (OSA) can have negative impacts on the health outcomes of individuals with type 2 diabetes. However, in the United Arab Emirates (UAE), there is a lack of understanding regarding the relationship between OSA and type 2 diabetes despite the significant implications it has on health. The primary objective of this study is to investigate the association between OSA risk and type 2 diabetes, associated risk factors, and gender differences in OSA symptoms among Emirati adults.We conducted a cross-sectional analysis of the baseline data from the UAE Healthy Future Study (UAEHFS) collected between February 2016 and March 2023. Our sample consisted of 4578 participants aged 18-71 who completed the STOP-BANG survey, provided body measurements and blood samples. We stratified the patients according to their OSA risk and diabetes. We used univariate and multivariate logistic regression models to analyze the relationship between OSA risk and type 2 diabetes and to identify factors associated with risk for OSA and type 2 diabetes. We estimated odds ratios (ORs) with corresponding 95% confidence intervals (95% CI).The mean age was 27.5 years (± 8.35), and 55.81% (n=2555) were men. The overall prevalence of high risk for OSA was 16.58% and was higher in men compared to women (26.46% vs 4.10%). Women reported feeling tired more often than men (68.02% vs 48.96%). Both genders have similar rates of stop breathing and BMI ≥ 35. There was a significant association between the OSA risk and type 2 diabetes in the unadjusted model (OR=2.44; 95% CI: 1.78-3.35; p-value <0.0001) and (OR=6.44; 95% CI: 4.32-9.59; p-value < 0.0001) among those who reported intermediate and high OSA risk, respectively. After adjusting the model for education attainment, marital status, waist circumference, and smoking, the association remained significant between diabetes and OSA risk, with an OR of 1.65 (95%CI: 1.18-2.32; p-value =0.004) for intermediate OSA risk and 3.44 (95%CI: 2.23-5.33; p-value <0.0001) for high OSA risk.This study conducted in the UAE found a significant correlation between OSA risk and type 2 diabetes. We suggest introducing routine screening of OSA for individuals with diabetes.","PeriodicalId":505784,"journal":{"name":"Frontiers in Endocrinology","volume":"6 6","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Association between obstructive sleep apnea risk and type 2 diabetes among Emirati adults: results from the UAE healthy future study\",\"authors\":\"Manal Taimah, Amar Ahmad, Mohammad Al-Houqani, Abdullah Al Junaibi, Youssef Idaghdour, A. Abdulle, Raghib Ali\",\"doi\":\"10.3389/fendo.2024.1395886\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Obstructive sleep apnea (OSA) can have negative impacts on the health outcomes of individuals with type 2 diabetes. However, in the United Arab Emirates (UAE), there is a lack of understanding regarding the relationship between OSA and type 2 diabetes despite the significant implications it has on health. The primary objective of this study is to investigate the association between OSA risk and type 2 diabetes, associated risk factors, and gender differences in OSA symptoms among Emirati adults.We conducted a cross-sectional analysis of the baseline data from the UAE Healthy Future Study (UAEHFS) collected between February 2016 and March 2023. Our sample consisted of 4578 participants aged 18-71 who completed the STOP-BANG survey, provided body measurements and blood samples. We stratified the patients according to their OSA risk and diabetes. We used univariate and multivariate logistic regression models to analyze the relationship between OSA risk and type 2 diabetes and to identify factors associated with risk for OSA and type 2 diabetes. We estimated odds ratios (ORs) with corresponding 95% confidence intervals (95% CI).The mean age was 27.5 years (± 8.35), and 55.81% (n=2555) were men. The overall prevalence of high risk for OSA was 16.58% and was higher in men compared to women (26.46% vs 4.10%). Women reported feeling tired more often than men (68.02% vs 48.96%). Both genders have similar rates of stop breathing and BMI ≥ 35. There was a significant association between the OSA risk and type 2 diabetes in the unadjusted model (OR=2.44; 95% CI: 1.78-3.35; p-value <0.0001) and (OR=6.44; 95% CI: 4.32-9.59; p-value < 0.0001) among those who reported intermediate and high OSA risk, respectively. After adjusting the model for education attainment, marital status, waist circumference, and smoking, the association remained significant between diabetes and OSA risk, with an OR of 1.65 (95%CI: 1.18-2.32; p-value =0.004) for intermediate OSA risk and 3.44 (95%CI: 2.23-5.33; p-value <0.0001) for high OSA risk.This study conducted in the UAE found a significant correlation between OSA risk and type 2 diabetes. 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引用次数: 0
摘要
阻塞性睡眠呼吸暂停(OSA)会对 2 型糖尿病患者的健康产生负面影响。然而,在阿拉伯联合酋长国(UAE),人们对 OSA 与 2 型糖尿病之间的关系缺乏了解,尽管它对健康有重大影响。本研究的主要目的是调查 OSA 风险与 2 型糖尿病之间的关系、相关风险因素以及阿联酋成年人 OSA 症状的性别差异。我们对 2016 年 2 月至 2023 年 3 月期间收集的阿联酋健康未来研究(UAEHFS)基线数据进行了横断面分析。我们的样本包括 4578 名 18-71 岁的参与者,他们完成了 STOP-BANG 调查,提供了身体测量数据和血液样本。我们根据 OSA 风险和糖尿病对患者进行了分层。我们使用单变量和多变量逻辑回归模型分析了OSA风险与2型糖尿病之间的关系,并确定了与OSA和2型糖尿病风险相关的因素。平均年龄为 27.5 岁(± 8.35),55.81%(n=2555)为男性。OSA高危人群的总体患病率为16.58%,男性高于女性(26.46% vs 4.10%)。女性比男性更经常感到疲劳(68.02% 对 48.96%)。两性的呼吸停止率和体重指数≥35的比例相似。在未调整模型中(OR=2.44;95% CI:1.78-3.35;p 值<0.0001),OSA 风险与 2 型糖尿病之间存在明显关联,在报告中等和高 OSA 风险的人群中,OSA 风险与 2 型糖尿病之间也存在明显关联(OR=6.44;95% CI:4.32-9.59;p 值<0.0001)。在根据教育程度、婚姻状况、腰围和吸烟情况对模型进行调整后,糖尿病与 OSA 风险之间的关系仍然显著,中度 OSA 风险的 OR 为 1.65(95%CI:1.18-2.32;p 值 =0.004),高度 OSA 风险的 OR 为 3.44(95%CI:2.23-5.33;p 值 <0.0001)。我们建议对糖尿病患者进行OSA常规筛查。
Association between obstructive sleep apnea risk and type 2 diabetes among Emirati adults: results from the UAE healthy future study
Obstructive sleep apnea (OSA) can have negative impacts on the health outcomes of individuals with type 2 diabetes. However, in the United Arab Emirates (UAE), there is a lack of understanding regarding the relationship between OSA and type 2 diabetes despite the significant implications it has on health. The primary objective of this study is to investigate the association between OSA risk and type 2 diabetes, associated risk factors, and gender differences in OSA symptoms among Emirati adults.We conducted a cross-sectional analysis of the baseline data from the UAE Healthy Future Study (UAEHFS) collected between February 2016 and March 2023. Our sample consisted of 4578 participants aged 18-71 who completed the STOP-BANG survey, provided body measurements and blood samples. We stratified the patients according to their OSA risk and diabetes. We used univariate and multivariate logistic regression models to analyze the relationship between OSA risk and type 2 diabetes and to identify factors associated with risk for OSA and type 2 diabetes. We estimated odds ratios (ORs) with corresponding 95% confidence intervals (95% CI).The mean age was 27.5 years (± 8.35), and 55.81% (n=2555) were men. The overall prevalence of high risk for OSA was 16.58% and was higher in men compared to women (26.46% vs 4.10%). Women reported feeling tired more often than men (68.02% vs 48.96%). Both genders have similar rates of stop breathing and BMI ≥ 35. There was a significant association between the OSA risk and type 2 diabetes in the unadjusted model (OR=2.44; 95% CI: 1.78-3.35; p-value <0.0001) and (OR=6.44; 95% CI: 4.32-9.59; p-value < 0.0001) among those who reported intermediate and high OSA risk, respectively. After adjusting the model for education attainment, marital status, waist circumference, and smoking, the association remained significant between diabetes and OSA risk, with an OR of 1.65 (95%CI: 1.18-2.32; p-value =0.004) for intermediate OSA risk and 3.44 (95%CI: 2.23-5.33; p-value <0.0001) for high OSA risk.This study conducted in the UAE found a significant correlation between OSA risk and type 2 diabetes. We suggest introducing routine screening of OSA for individuals with diabetes.