Dr. S M Saadi, Dr. Rehnuma Taher Fariha, Dr. Rabeya Sultana Jui, Dr. S M Sadlee, Dr. Pijush Majumder, Dr. Muhammad Abdur Rouf, Dr. Biplob Kumar Roy, Dr. Md. Nazrul Islam, Dr. Amitabh Sarkar
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引用次数: 0
摘要
勃起功能障碍(ED)是影响全球成年男性的一种普遍病症,其特点是无法达到或维持足以进行性交的勃起。多发性硬化症、帕金森病、缺血性中风、先天性脊柱异常和脊髓损伤等神经系统疾病会破坏勃起功能所必需的神经通路。此外,糖尿病、高血压、高脂血症和心血管疾病等慢性疾病,以及吸烟和饮酒等生活方式因素都会损害血管健康,从而加剧 ED。心理压力使 ED 的病因进一步复杂化。骨盆手术、海绵体神经损伤和某些药物(包括降压药和抗抑郁药)也会导致 ED 的恶化。有效的治疗需要解决这些神经、血管、荷尔蒙和心理因素,因此需要神经科、泌尿科、内分泌科和精神卫生专业人员等多学科专家的参与。这篇综述强调了在 ED 的病理生理学中,神经系统疾病、全身性疾病和生活方式因素之间复杂的相互作用,强调需要针对潜在的致病因素采取量身定制的治疗策略,以改善患者的预后。
Erectile Dysfunction in Adults: A Review of Neurological Causes and Risk Factor Analysis
Erectile dysfunction (ED) is a prevalent condition affecting adult men globally, characterized by the inability to achieve or maintain an erection sufficient for sexual intercourse. Neurological causes, including multiple sclerosis, Parkinson's disease, ischemic stroke, congenital spinal abnormalities, and spinal cord injuries, disrupt neural pathways essential for erectile function. Additionally, chronic conditions such as diabetes mellitus, hypertension, hyperlipidemia, and cardiovascular diseases, along with lifestyle factors like smoking and alcohol consumption, exacerbate ED by compromising vascular health. Psychological stressors further complicate the etiology of ED. Pelvic surgeries, cavernous nerve injuries, and certain medications, including antihypertensives and antidepressants, contribute to ED progression. Effective management requires addressing these neurological, vascular, hormonal, and psychological factors, necessitating a multidisciplinary approach involving specialists such as neurologists, urologists, endocrinologists, and mental health professionals. This review highlights the complex interplay between neurological disorders, systemic conditions, and lifestyle factors in the pathophysiology of ED, emphasizing the need for tailored treatment strategies targeting the underlying contributors to improve patient outcomes.