常见变异性免疫缺陷症--在资源有限的环境中被误诊的延迟诊断病例

S. Raina, Tanya Thakur, Korada Vivek Naidu, Bikram Shah, Manoj Thakur
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引用次数: 0

摘要

我们报告了一例常见变异性免疫缺陷病(CVID)病例,患者是一名 42 岁女性,过去十年来一直反复发作鼻炎。患者在过去一年中出现咳嗽和进行性呼吸困难。患者因社区获得性肺炎入院,痰培养铜绿假单胞菌阳性。常见变异性免疫缺陷症是在患者发病十年后才确诊的。CVID 是一种诊断不足的疾病,原因是发展中国家的怀疑指数低、缺乏认识、检查设施差以及传染病发病率较高。对于反复发作的鼻炎或肺炎患者,应怀疑是否患有 CVID,并建议对血清免疫球蛋白进行评估。
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Common variable immunodeficiency- A delayed diagnosis of an underdiagnosed entity in resource limited setting
We report a case of common variable immunodeficiency (CVID) in a 42-year-old female who presented with history of recurrent rhinosinusitis for the last ten years. Patient had developed cough and progressive dyspnoea for last one year. Patient was admitted with community acquired pneumonia and sputum culture was positive for Pseudomonas aeruginosa. Common variable immunodeficiency was diagnosed ten years after the onset of symptoms. CVID is an underdiagnosed disorder because of the low index of suspicion, lack of awareness, poor facilities for the investigations and higher prevalence of infectious diseases in developing countries. CVID should be suspected in patients with recurrent rhinosinusitis or pneumonia and evaluation of serum immunoglobulins is advised.
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