Madhu Gupta, A. Bansal, Aprajita Mehta, Nikita Sharma
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引用次数: 0
摘要
我们通过 PubMed、Embase 和 Google Scholar 搜索引擎对已发表的文章(截至 2023 年 10 月)进行了全面的文献综述,以界定印度成人免疫接种的需求、推荐的成人疫苗、成人免疫接种的障碍、未来的研究领域和前进方向。从 PubMed、Embase 和 Google Scholar 上共筛选出 29,894 篇文章。其中,对 53 篇文章进行了全文审查。研究结果强调了印度成人免疫接种的必要性,因为患有合并症、免疫衰老、免疫力下降的脆弱老年人口不断增加,前列腺增生症发病率上升导致他们的发病率和死亡率升高,住院费用增加以及抗菌药耐药性的出现。推荐的成人疫苗包括人类乳头瘤病毒疫苗、肺炎球菌疫苗、流感疫苗和伤寒疫苗,分别针对健康成人和特殊人群。所面临的挑战包括:国家疫苗接种政策未将其列为优先事项、医疗保健提供者对疫苗接种认识不足以及疫苗接种犹豫不决。
Need and Rationale of the Adult Immunisation in India: A Review
A comprehensive literature review of published articles (till October 2023) was done through PubMed, Embase and Google Scholar search engines to delineate the need for adult immunisation, recommended adult vaccines, barriers to adult immunisation, future research areas and way forward in the Indian context. A total of 29,894 articles were screened from PubMed, Embase and Google Scholar. Of these, a full-text review of 53 articles was done. The findings emphasised the need for adult immunisation in India because of the growing vulnerable elderly population with comorbidities, immunosenescence, waning immunity, rising incidence of VPDs leading to higher morbidity and mortality amongst them, rising cost of hospitalisation and the emergence of antimicrobial resistance. The recommended adult vaccines include human papilloma virus vaccine, pneumococcal vaccine, influenza and typhoid vaccine for healthy adults and special population groups, respectively. Challenges include less prioritisation in the National Vaccination Policy, insufficient awareness amongst healthcare providers and vaccine hesitancy.