Xingyu Bai, Daixu Wang, Liyun Zhen, Meng Cui, Jingquan Liu, Ning Zhao, Chengkuo Lee, Bin Yang
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Design and micromanufacturing technologies of focused piezoelectric ultrasound transducers for biomedical applications
Piezoelectric ultrasonic transducers have shown great potential in biomedical applications due to their high acoustic-to-electric conversion efficiency and large power capacity. The focusing technique enables the transducer to produce an extremely narrow beam, greatly improving the resolution and sensitivity. In this work, we summarize the fundamental properties and biological effects of the ultrasound field, aiming to establish a correlation for device design and application. Focusing techniques for piezoelectric transducers are highlighted, including material selection and fabrication methods, which determine the final performance of piezoelectric transducers. Numerous examples from ultrasound imaging, neuromodulation, tumor ablation to ultrasonic wireless energy transfer are summarized to highlight the great promise of biomedical applications. Finally, the challenges and opportunities of focused ultrasound transducers are presented. The aim of this review is to bridge the gap between focused ultrasound systems and biomedical applications.
期刊介绍:
The International Journal of Extreme Manufacturing (IJEM) focuses on publishing original articles and reviews related to the science and technology of manufacturing functional devices and systems with extreme dimensions and/or extreme functionalities. The journal covers a wide range of topics, from fundamental science to cutting-edge technologies that push the boundaries of currently known theories, methods, scales, environments, and performance. Extreme manufacturing encompasses various aspects such as manufacturing with extremely high energy density, ultrahigh precision, extremely small spatial and temporal scales, extremely intensive fields, and giant systems with extreme complexity and several factors. It encompasses multiple disciplines, including machinery, materials, optics, physics, chemistry, mechanics, and mathematics. The journal is interested in theories, processes, metrology, characterization, equipment, conditions, and system integration in extreme manufacturing. Additionally, it covers materials, structures, and devices with extreme functionalities.