An efficient synthesis of new pyrazolone-substituted C-acylimine derivatives by three-component reaction between arylglyoxal derivatives, arylamines and pyrazolone

An effective protocol for synthesis of some new pyrazolone-substituted C-acylimine derivatives is reported through a one-pot three-component reaction between arylglyoxals, aniline derivatives and pyrazolone. All reactions were conducted in ethanol/acetic acid mixture as solvent and the stable products were obtained by simple filtering off the precipitated solids in high yields. The structures of all products were proved by 1 H and 13 C NMR and IR spectral and elemental analysis data